Evidence map›Paper›PMID 35681386›Full record

ArticleFoods (Basel, Switzerland)2022

Evaluation of the Putative Duplicity Effect of Novel Nutraceuticals Using Physico-Chemical and Biological In Vitro Models.

Bianca-Maria Tihăuan, Mădălina Axinie Bucos, Ioana-Cristina Marinaș, Ionela Avram, Anca-Cecilia Nicoară, Grațiela Grădișteanu-Pîrcălăbioru, Georgiana Dolete, Ana-Maria Ivanof, Tatiana Onisei, Angela Cășărică and 1 more

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Bianca-Maria TihăuanLife, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest, 050096 Bucharest, Romania.ORCID 0000-0001-6288-0267
Mădălina Axinie BucosResearch & Development for Advanced Biotechnologies and Medical Devices, SC Sanimed International Impex SRL, 087040 Călugăreni, Romania.ORCID 0000-0002-3546-1136
Ioana-Cristina MarinașLife, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest, 050096 Bucharest, Romania.ORCID 0000-0002-7342-5398
Ionela AvramDepartment of Genetics, Faculty of Biology, University of Bucharest, 030018 Bucharest, Romania.ORCID 0000-0002-9171-0846
Anca-Cecilia NicoarăFaculty of Pharmacy, University of Medicine and Pharmacy "Carol Davila", 020021 Bucharest, Romania.
Grațiela Grădișteanu-PîrcălăbioruLife, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest, 050096 Bucharest, Romania.
Georgiana DoleteDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-9924-1987
Ana-Maria IvanofLife, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest, 050096 Bucharest, Romania.
Tatiana OniseiNational Institute of Research & Development for Food Bioresources-IBA Bucharest, 020323 Bucharest, Romania.
Angela CășăricăNational Institute for Chemical-Pharmaceutical Research and Development, 031282 Bucharest, Romania.
Lucia PîrvuNational Institute for Chemical-Pharmaceutical Research and Development, 031282 Bucharest, Romania.ORCID 0000-0002-5032-5079
University of Bucharest · RONational Institute For Chemical Pharmaceutical Research and Development · ROUniversitatea Națională de Știință și Tehnologie Politehnica București · ROCarol Davila University of Medicine and Pharmacy · RONational Institute for Research and Development in Informatics - ICI Bucharest · RO

Funding

Ministry of European Investments and Projects, Competitiveness Operational Programme ID P_40_406, SMIS 105542, Subsidiary Contract D no. 04/ 23.03.2021Regional Development Fund (ERDF), Competitiveness Operational Programme Contract no. 327/390003/06-11-2020, SMIS 126867
6 · The paper itself

Abstract

Nutraceuticals are experiencing a high-rise use nowadays, which is incomparable to a few years ago, due to a shift in consumers' peculiarity tendencies regarding the selection of alternatives to Western medicine, potential immunity boosters, or gut-health promoters. Nutraceuticals' compositions and actual effects should be proportional to their sought-after status, as they are perceived to be the middle ground between pharma rigor and naturally occurring actives. Therefore, the health benefits via nutrition, safe use, and reduction of potential harm should be the main focus for manufacturers. In this light, this study assess the nutritional profile (proteins, fats, fibers, caloric value, minerals) of a novel formulated nutraceutical, its physico-chemical properties, FTIR spectra, antioxidant activity, anthocyanins content, and potential hazards (heavy metals and microbiological contaminants), as well as its cytotoxicity, adherence, and invasion of bacteria on HT-29 cells, as well as its evaluation of beneficial effect, potential prebiotic value, and duplicity effect on gut microbiota in correlation with Regulation (EC) No 1924/2006. The results obtained indicate the growth stimulation of

Indexed as

antioxidantdietgut healthnutraceuticalsprebiotics

Identifiers

PMID35681386
PMCPMC9180833
OpenAlexW4281740539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.