ArticleBMC oral health2022
The antibacterial effect of silver, zinc-oxide and combination of silver/ zinc oxide nanoparticles coating of orthodontic brackets (an in vitro study).
Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Use of Antimicrobial Silver Coatings on Fixed Orthodontic Appliances, Including Archwires, Brackets, and Microimplants: A Systematic Review.Medical science monitor : international medical journal of experimental and clinical research · 2024Pooled it
- Evaluation of zinc oxide nanoparticle coated elastomeric modules and it's effect on Streptococcus mutans concentration and enamel mineralization - A randomized split mouth trial.Scientific reports · 2025Trial
- Antibacterial Interventions for Orthodontic Appliances; Surface Modifications, Coatings and Bulk-Incorporated Antibacterial Agents: Materials, Mechanisms and Clinical Application-A Scoping Review.Materials (Basel, Switzerland) · 2026Review
- Cuttlefish Ink-Derived Melanin Nanoparticles Enabling NIR-Responsive Electrospun Nanofibrous Mats for On-Demand Selective Antibacterial Disinfection of Orthodontic Braces.ACS applied materials & interfaces · 2026Article
- Nanostructured implants for enhanced integration and localized therapy.BioImpacts : BI · 2026Review
- Evaluating antibacterial efficiency of orthodontic brackets coated with copper oxide, titanium dioxide and silver nanoparticles.Bioinformation · 2026Article
- An overview of types of antibacterial coatings and methods for creating them on orthodontic wires.Journal of materials science. Materials in medicine · 2025Review
- Usage of Silver Nanoparticles in Orthodontic Appliances.Materials (Basel, Switzerland) · 2025Review
- Functional characterization of orthodontic bands coated with chitosan-zinc oxide nanocomposite: antibacterial and electrochemical characterization.BMC oral health · 2025Article
- Article
- Honey Compounds Exhibit Antibacterial Effects AgainstAntibiotics (Basel, Switzerland) · 2025Article
- Enhanced anti-microbial properties of clear aligner resin containing zwitterionic material.Scientific reports · 2025Article
- Evaluation of the efficacy of P11-4 and CCP-ACPF in the prevention and treatment of white spot lesions: a multi-technique approach.Scientific reports · 2025Article
- Herbal remedies for oral and dental health: a comprehensive review of their multifaceted mechanisms including antimicrobial, anti-inflammatory, and antioxidant pathways.Inflammopharmacology · 2025Review
- The potential of ceramic nanomaterials in preventive dentistry.Nanomedicine (London, England) · 2025Article
- In vitro evaluation of silver-zinc oxide-eugenol nanocomposite for enhanced antimicrobial and wound healing applications in diabetic conditions.Discover nano · 2025Article
- A novel stable biomimetic adhesive coating for functionalization of orthodontic brackets against bacterial colonization and white spot lesions.BMC oral health · 2025Article
- Evaluation of antibacterial efficacy and surface roughness of orthodontic brackets coated with silver-copper hybrid or zinc oxide nanoparticles: AnJournal of orthodontic science · 2025Article
- Nanocarriers and Nanomaterials in Dentistry: A Review on Common Dental Issues and their Management.Current pharmaceutical design · 2025Review
- Effect of Quaternary Ammonium-Based Antimicrobial Coating on the Mechanical Properties and Bacterial Adhesion to Gummetal Archwire.International journal of dentistry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreventive measures are essential during the length of orthodontic treatment to reduce the risk of decalcification and white spot lesions formation. With the evolution of procedures that enable coating of the orthodontic brackets using nanoparticles known for their good antibacterial activity, coating the brackets with nanoparticles of silver, zinc oxide and combination of silver and zinc oxide to evaluate their antibacterial effect in comparison to a control group without coating was carried out in this study.
methodsFour groups of 12 brackets each were included in the study. The coating procedure was carried out using physical vapor deposition. The antibacterial activity was tested on Streptococcus mutans and Lactobacillus Acidophilus using colony forming count. The antibacterial activity was evaluated immediately after coating and later after 3 months.
resultsBrackets coated with combination of silver and zinc oxide nanoparticles had the highest ability on reduction of both Streptococcus mutans and Lactobacillus Acidophilus count followed by silver nanoparticles and then zinc oxide nanoparticles. No significant difference was found between the first and second antibacterial tests.
conclusionThe silver/zinc oxide nanoparticles coated brackets had the highest antibacterial effect in comparison to silver nanoparticles and zinc oxide nanoparticles individually coated brackets on Streptococcus mutans and Lactobacillus acidophilus, and all types of coatings showed enhanced antibacterial effect in comparison to the uncoated bracket. Coating of orthodontic brackets could be further assessed in clinical application to prevent decalcification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.