Evidence map›Paper›PMID 35681126›Full record

ArticleBMC genomics2022

CircVIS: a platform for circRNA visual presentation.

Ya-Chi Lin, Yun-Chin Wang, Yueh-Chun Lee, Hui-Hsuan Lin, Kai-Li Chang, Yu-Chieh Tai, Kuei-Yang Hsiao

Abstract read
In one paragraph

Article in BMC genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Translation of circular RNAs.Nucleic acids research · 2025
    Review
  3. Article
  4. Article
  5. Optimal design of synthetic circular RNAs.Experimental & molecular medicine · 2024
    Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ya-Chi Lin *Department of Plant Pathology, College of Agriculture and Natural Resources, National Chung Hsing University, Taichung, 40227, Taiwan.ORCID http://orcid.org/0000-0003-1240-7011
Yun-Chin Wang *Bachelor Program of Biotechnology, College of Agriculture and Natural Resources, National Chung Hsing University, Taichung, 40227, Taiwan.ORCID http://orcid.org/0000-0003-1776-8684
Yueh-Chun Lee *Department of Radiation Oncology, Chung Shan Medical University Hospital, Taichung, 40201, Taiwan.ORCID http://orcid.org/0000-0002-9713-9708
Hui-Hsuan LinProgram in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, 40227, Taiwan.ORCID http://orcid.org/0000-0002-8488-3845
Kai-Li ChangDepartment of Physiology, National Cheng Kung University, Tainan, 70101, Taiwan.ORCID http://orcid.org/0000-0002-1648-8755
Yu-Chieh TaiDepartment of Bioengineering, University of California, Berkeley, 94720, USA.ORCID http://orcid.org/0000-0003-1418-8270
Kuei-Yang HsiaoBachelor Program of Biotechnology, College of Agriculture and Natural Resources, National Chung Hsing University, Taichung, 40227, Taiwan. ky.hsiao@nchu.edu.tw.ORCID http://orcid.org/0000-0002-1648-974X

Funding

Hsing Chung inter-institutional Project (TW) -10906Hsing Chung inter-institutional Project (TW) -11007Hsing Chung inter-institutional Project (TW) NCHU-CSMU-10805Ministry of Science and Technology, Taiwan MOST 109-2320-B-005-008-MY3
6 · The paper itself

Abstract

backgroundThe collection of circRNAs mostly focused on their sequence composition such as protein/miRNA binding motif, and/or regulatory elements such as internal ribosome entry site. However, less attention was paid to subcellular localization. CircVIS aimed to provide a collection of circRNAs with information of subcellular compartments and also integrated the circRNA entries from previous circRNA databases.

resultsA collection of circRNAs from public circRNA databases and de novo identification were annotated according to subcellular localizations including nucleoplasm, chromatin-associated parts, cytoplasm and polyribosome. All circRNAs were aligned to a selected major transcript, and if presence, the circRNA-derived open reading frame with annotation of functional domain were compared to its parental protein. The results showed that distinct circRNAs may exert their molecular and cellular functions in different subcellular compartments. The web service is made freely available at http://lab-x-omics.nchu.edu.tw/circVIS .

conclusionsCircVIS allows users to visualize the alignment between a given circRNA and its most relevant reference transcript along with information of subcellular localization.

Indexed as

MicroRNAsRNA, CircularInternal Ribosome Entry SitesOpen Reading FramesProteinsRNAInternal Ribosome Entry SitesMicroRNAsProteinsRNARNA, CircularBackspliceChromatin-associatedCircular RNACoding circRNAPolyribosomePolysomeReference transcriptSubcellular localization

Identifiers

PMID35681126
PMCPMC9185860

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.