ArticleSpinal cord2022
Heart rate changes associated with autonomic dysreflexia in daily life of individuals with chronic spinal cord injury.
Article in Spinal cord, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Blood pressure variability in daily life: comparing individuals with cervical and upper-thoracic spinal cord injury to non-injured controls.Journal of human hypertension · 2026Article
- Evaluation and management of autonomic functions in patients with spinal cord injury: A scoping review.The journal of spinal cord medicine · 2026Article
- Robust learning framework for a scalable remote monitoring of autonomic dysreflexia: use-case in spinal cord injury.Scientific reports · 2026Article
- Dysreflexic dilemma: do we need a revised definition for autonomic dysreflexia?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Autonomic dysreflexia with relative tachycardia: Potential physiologic pathways for this head scratching clinical finding.PM & R : the journal of injury, function, and rehabilitation · 2025Article
- Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation-Mapping for a Blood Pressure Response: A Case Series.Neurotrauma reports · 2024Article
- Cerebrovascular Reactivity Following Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2024Article
- Cardiovascular and cerebrovascular responses to urodynamics testing after spinal cord injury: The influence of autonomic injury.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designSecondary data analysis.
objectiveTo characterize heart rate (HR) changes during autonomic dysreflexia (AD) in daily life for individuals with chronic spinal cord injury (SCI).
settingUniversity-based laboratory/community-based outpatient.
methodsCardiovascular data, previously collected during a 24-h ambulatory surveillance period in individuals with chronic SCI, were assessed. Any systolic blood pressure (SBP) increase ≥20 mmHg from baseline was identified and categorized into confirmed AD (i.e., diarized trigger), unknown (i.e., no diary entry), or unlikely AD (i.e., potential exertion driven SBP increase) groups. SBP-associated HR changes were categorized as unchanged, increased or decreased compared to baseline.
resultsForty-five individuals [8 females, median age and time since injury of 43 years (lower and upper quartiles 36-50) and 17 years (6-23), respectively], were included for analysis. Overall, 797 episodes of SBP increase above AD threshold were identified and classified as confirmed (n = 250, 31.4%), unknown (n = 472, 59.2%) or unlikely (n = 75, 9.4%). The median number of episodes per individual within the 24-h period was 13 (8-28). HR-decrease/increase ratio was 3:1 for confirmed and unknown, and 1.5:1 for unlikely episodes. HR changes resulting in brady-/tachycardia were 34.4%/2.8% for confirmed, 39.6%/3.4% unknown, and 26.7%/9.3% for unlikely episodes, respectively.
conclusionsOur findings suggest that the majority of confirmed AD episodes are associated with a HR decrease. Using wearable-sensors-derived measures of physical activity in future studies could provide a more detailed characterization of HR changes during AD and improve AD identification.
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