Evidence map›Paper›PMID 35680284›Full record

ArticleBMJ case reports2022

Paediatric acute haemorrhagic leukoencephalitis.

Harshita Bamnawat, Daisy Khera, Siyaram Didel, Sarbesh Tiwari

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Harshita BamnawatPediatrics, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Daisy KheraPediatrics, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India pushpinderdaisy@gmail.com.ORCID http://orcid.org/0000-0003-4356-6883
Siyaram DidelPediatrics, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.ORCID http://orcid.org/0000-0003-4578-2184
Sarbesh TiwariRadiodiagnosis, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
All India Institute of Medical Sciences Jodhpur · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a preschool age girl, previously healthy, referred to our hospital on ventilatory support with a history of vomiting, headache, and rapid neurological worsening within 24 hours in the form of seizures, encephalopathy and loss of consciousness. On presentation, she was deeply comatose with dilated non-reactive pupils, absent brainstem reflexes and flaccid quadriplegia. Diagnosis of acute haemorrhagic leukoencephalitis was considered based on laboratory and neuroimaging findings. MRI of the brain showed fluffy white matter hyperintensities and microhaemorrhages in bilateral cerebral hemispheres and thalami. Aggressive treatment with methylprednisolone, plasmapheresis and intravenous immunoglobulin showed dramatic improvement with no neurological sequelae. Our case is unique in a way that despite the hyperacute onset and rapid deterioration, with a fulminant course in the intensive care unit, the child recovered dramatically with aggressive management.

Indexed as

Leukoencephalitis, Acute HemorrhagicBrainChildChild, PreschoolComaFemaleHumansMagnetic Resonance ImagingSeizuresNeurology (drugs and medicines)Paediatric intensive carePaediatrics (drugs and medicines)

Identifiers

PMID35680284
PMCPMC9185211
OpenAlexW4281788100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.