ArticleAJNR. American journal of neuroradiology2022
RAPID CT Perfusion-Based Relative CBF Identifies Good Collateral Status Better Than Hypoperfusion Intensity Ratio, CBV-Index, and Time-to-Maximum in Anterior Circulation Stroke.
Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 29 citations in OpenAlex.
- Article
- Predictors of Unfavorable Outcome After Endovascular Thrombectomy for Acute Basilar Artery Occlusion with Mild Symptoms.Clinical neuroradiology · 2026Article
- Developmental timing matters: enhancing longitudinal and mechanistic research on neurovascular coupling in maltreatment-related depression.European child & adolescent psychiatry · 2026Article
- Quantitative validation of a CT perfusion-derived corrected CBV index as a surrogate of angiographic collateral status(ASITN/SIR grading) in anterior circulation ischemia.Neurosurgical review · 2026Article
- Venous-phase Tan-based collateral assessment on CTP-derived CTA for outcome stratification after reperfusion therapy in acute ischemic stroke.Frontiers in neurology · 2026Article
- Unfavorable Perfusion Collateral Impairment Score Is Associated with Higher Odds of Poor Outcomes in Large Vessel Occlusion Stroke.Stroke (Hoboken, N.J.) · 2025Article
- Collateral Status Evaluation Using CT Angiography and Perfusion Source Images in Acute Stroke Patients.Brain sciences · 2025Article
- Integrating perfusion imaging derived venous outflow and tissue-level collateral parameters in a comprehensive clinical model enhances prognostication in large vessel occlusion stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Prolonged Venous Transit as a Superior Predictor of Functional Outcomes in Successfully Reperfused Large Vessel Occlusions: Comparative Analysis With Cerebral Blood Volume Index and Hypoperfusion Intensity Ratio.Journal of the American Heart Association · 2025Article
- Mismatch Vs No Mismatch in Large Core-A Matter of Definition.Clinical neuroradiology · 2025Article
- Factors associated with short-term recurrent ischemic stroke: culprit plaque, collateral circulation, and pathological mechanisms.Frontiers in neurology · 2025Article
- Perfusion-Based Relative Cerebral Blood Volume Is Associated With Functional Dependence in Large-Vessel Occlusion Ischemic Stroke.Journal of the American Heart Association · 2024Article
- Effects of intracranial artery stenosis of anterior circulation on cognition-A CT perfusion-based study.Brain and behavior · 2024Article
- High relative cerebral blood volume is associated with good long term clinical outcomes in acute ischemic stroke: a retrospective cohort study.BMC neurology · 2024Article
- Relative Cerebral Blood Flow as an Indirect Imaging Surrogate in Patients With Anterior Circulation Large Vessel Occlusion and Association of Baseline Characteristics With Poor Collateral Status.Journal of the American Heart Association · 2024Article
- CT perfusion based rCBF <38% volume is independently and negatively associated with digital subtraction angiography collateral score in anterior circulation large vessel occlusions.The neuroradiology journal · 2024Article
- Pretreatment parameters associated with hemorrhagic transformation among successfully recanalized medium vessel occlusions.Journal of neurology · 2024Article
- The Relative Cerebral Blood Volume (rCBV) < 42% Is Independently Associated with Collateral Status in Anterior Circulation Large Vessel Occlusion.Journal of clinical medicine · 2024Article
- Uncertainty-aware deep learning for trustworthy prediction of long-term outcome after endovascular thrombectomy.Scientific reports · 2024Article
- Patchy profile sign in RAPID software: a specific marker for intracranial atherosclerotic stenosis in acute ischemic stroke.Frontiers in neurology · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeInformation of collateral flow may help to determine eligibility for thrombectomy. Our aim was to identify CT perfusion-based surrogate parameters of good collateral status in acute anterior circulation ischemic stroke. MATERIALS AND
methodsIn this retrospective study, we assessed the collateral status of 214 patients who presented with acute ischemic stroke due to occlusion of the MCA M1 segment or the carotid terminus. Collaterals were assessed on dynamic CTA images analogous to the multiphase CTA score by Menon et al. CT perfusion parameters (time-to-maximum, relative CBF, hypoperfusion intensity ratio, and CBV-index) were assessed with RAPID software. The Spearman rank correlation and receiver operating characteristic analyses were performed to identify the parameters that correlate with collateral scores and good collateral supply (defined as a collateral score of ≥4).
resultsThe Spearman rank correlation was highest for a relative CBF < 38% volume (ρ = -0.66,
conclusionsAutomated CT perfusion analysis allows accurate identification of collateral status in acute ischemic stroke. A relative CBF < 38% may be a better perfusion-based indicator of good collateral supply compared with time-to-maximum, the hypoperfusion intensity ratio, and the CBV-index.
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