Evidence map›Paper›PMID 35680160›Full record

ArticleAJNR. American journal of neuroradiology2022

Asymmetry Matters: Diffusion Tensor Tractography of the Uncinate Fasciculus in Children with Verbal Memory Deficits.

S A Mohammad, N H Nashaat, A A M B Okba, A Kilany, A S Abdel-Rahman, A M Abd-Elhamed, E R Abdelraouf

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

S A MohammadFrom the Department of Diagnostic and Interventional Radiology and Molecular Imaging (S.A.M., A.A.M.B.O., A.S.A.-R., A.M.A.-E.), Faculty of Medicine, Ain Shams University, Cairo, Egypt Shaimaa_abdelsattar@med.asu.edu.eg.ORCID 0000-0003-4401-9814
N H NashaatResearch on Children with Special Needs Department (N.H.N., A.K., E.R.A.), Medical Research Division, National Research Centre, Cairo, Egypt.ORCID 0000-0003-1553-9327
A A M B OkbaFrom the Department of Diagnostic and Interventional Radiology and Molecular Imaging (S.A.M., A.A.M.B.O., A.S.A.-R., A.M.A.-E.), Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID 0000-0002-5094-9551
A KilanyResearch on Children with Special Needs Department (N.H.N., A.K., E.R.A.), Medical Research Division, National Research Centre, Cairo, Egypt.ORCID 0000-0002-3157-8396
A S Abdel-RahmanFrom the Department of Diagnostic and Interventional Radiology and Molecular Imaging (S.A.M., A.A.M.B.O., A.S.A.-R., A.M.A.-E.), Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID 0000-0002-4838-8767
A M Abd-ElhamedFrom the Department of Diagnostic and Interventional Radiology and Molecular Imaging (S.A.M., A.A.M.B.O., A.S.A.-R., A.M.A.-E.), Faculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID 0000-0003-2131-5856
E R AbdelraoufResearch on Children with Special Needs Department (N.H.N., A.K., E.R.A.), Medical Research Division, National Research Centre, Cairo, Egypt.ORCID 0000-0002-0899-8261
Ain Shams University · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeVerbal declarative memory performance relies on frontotemporal connectivity. The uncinate fasciculus is a major association tract connecting the frontal and temporal lobes. Hemispheric asymmetries contribute to various cognitive and neurobehavioral abilities. Here we investigated microstructural alterations and hemispheric asymmetry of the uncinate fasciculus and their possible correlation to memory performance of children with learning disorders attributed to verbal memory deficits. MATERIALS AND

methodsTwo groups of right-handed children with learning disorders attributed to verbal memory deficits and typically developing children (

resultsChildren with learning disorders showed absence of the normal left-greater-than-right asymmetry of fractional anisotropy and the normal right-greater-than-left asymmetry of radial diffusivity seen in typically developing children. Correlation with verbal memory subsets revealed that the higher the fractional anisotropy and asymmetry index, the better the rapid naming performance (

conclusionsThese findings demonstrated microstructural aberrations with reduction of hemispheric asymmetry of the uncinate fasciculus, which could disrupt the normal frontotemporal connectivity in children with learning disorders attributed to verbal memory deficits. This outcome gives more understanding of pathologic mechanisms underlying this disorder.

Indexed as

Learning DisabilitiesWhite MatterAnisotropyChildDiffusion Tensor ImagingHumansMemory DisordersUncinate Fasciculus

Identifiers

PMID35680160
PMCPMC9262073
OpenAlexW4282918494

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.