Evidence map›Paper›PMID 35680039›Full record

ArticleRespiratory physiology & neurobiology2022

Exploring inspiratory occlusion metrics to assess respiratory drive in patients under acute intermittent hypoxia.

Victoria R Rodrigues, Wendy L Olsen, Elaheh Sajjadi, Barbara K Smith, Nicholas J Napoli

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory physiology & neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Victoria R RodriguesUniversity of Florida, Department of Electrical and Computer Engineering, US; University of Florida, Human Informatics and Predictive Performance Optimization (HIPPO) Lab, US. Electronic address: victoria.ribeiro@ufl.edu.
Wendy L OlsenUniversity of Florida, Human Informatics and Predictive Performance Optimization (HIPPO) Lab, US; University of Florida, Breathing Research and Therapeutics Center, Department of Physiological Sciences, US. Electronic address: olsenwendy@ufl.edu.
Elaheh SajjadiUniversity of Florida, Department of Physical Therapy, US. Electronic address: elasajjadi1@gmail.com.
Barbara K SmithUniversity of Florida, Department of Physical Therapy, US; University of Florida, Breathing Research and Therapeutics Center, Department of Physiological Sciences, US. Electronic address: bksmith@phhp.ufl.edu.
Nicholas J NapoliUniversity of Florida, Department of Electrical and Computer Engineering, US; University of Florida, Human Informatics and Predictive Performance Optimization (HIPPO) Lab, US; University of Florida, Breathing Research and Therapeutics Center, Department of Physiological Sciences, US. Electronic address: n.napoli@ufl.edu.
University of Florida · USAmerican Physical Therapy Association · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Breathing Research and Therapeutics (BREATHE)T32HL134621 · NHLBI · UNIVERSITY OF FLORIDA · PI Gordon S. Mitchell · 2017 to 2026
$3.4M
NCATS NIH HHS UL1 TR001427NHLBI NIH HHS L30 HL159818NHLBI NIH HHS T32 HL134621
6 · The paper itself

Abstract

Patients living with Amyotrophic Lateral Sclerosis (ALS) experience respiratory weakness and, eventually, failure due to inspiratory motor neuron degeneration. Routine pulmonary function tests (e.g., maximum inspiratory pressure (MIP)) are used to assess disease progression and ventilatory compromise. However, these tests are poor discriminators between respiratory drive and voluntary respiratory function at rest. To better understand ALS disease progression, we can look into compensatory strategies and how patients consciously react to the occlusion and the effort produced to meet the ventilatory challenge of the occlusion. This ventilatory challenge, especially beyond the P

Indexed as

Amyotrophic Lateral SclerosisDisease ProgressionHumansHypoxiaPhrenic NerveRespiratory MusclesAcute intermittent hypoxiaAmyotrophic lateral sclerosisInspiratory pressureOcclusion pressureP(0.1)

Identifiers

PMID35680039
PMCPMC9749200
OpenAlexW4281614588

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.