Evidence map›Paper›PMID 35679803›Full record

ReviewCurrent opinion in plant biology2022

Elucidating the biology of transcription factor-DNA interaction for accurate identification of cis-regulatory elements.

Mohsen Hajheidari, Shao-Shan Carol Huang

Abstract readReview
In one paragraph

Review in Current opinion in plant biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Genome-Wide Characterization of thePlants (Basel, Switzerland) · 2026
    Article
  3. aBIOTECH · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Comprehensive analysis of HSF genes from celery (Frontiers in plant science · 2023
    Article
  20. International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mohsen HajheidariCenter for Genomics and Systems Biology, Department of Biology, New York University, 12 Waverly Pl, New York, NY 10003, USA.
Shao-Shan Carol HuangCenter for Genomics and Systems Biology, Department of Biology, New York University, 12 Waverly Pl, New York, NY 10003, USA. Electronic address: s.c.huang@nyu.edu.

Funding

Sequence, chromatin, and cellular contexts of transcription factor- DNA interaction and functionR35GM138143 · NIGMS · NEW YORK UNIVERSITY · PI Shao-shan Carol Huang · 2020 to 2026
$2.4M
NIGMS NIH HHS R35 GM138143
6 · The paper itself

Abstract

Transcription factors (TFs) play a critical role in determining cell fate decisions by integrating developmental and environmental signals through binding to specific cis-regulatory modules and regulating spatio-temporal specificity of gene expression patterns. Precise identification of functional TF binding sites in time and space not only will revolutionize our understanding of regulatory networks governing cell fate decisions but is also instrumental to uncover how genetic variations cause morphological diversity or disease. In this review, we discuss recent advances in mapping TF binding sites and characterizing the various parameters underlying the complexity of binding site recognition by TFs.

Indexed as

DNATranscription FactorsBinding SitesBiologyProtein BindingDNATranscription FactorsCis-regulatory elementsGene regulationTranscriptional regulationTranscription factor-DNA interactionTranscription factors

Identifiers

PMID35679803
PMCPMC10103634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.