ReviewInternational journal of epidemiology2022
Sample size calculators for planning stepped-wedge cluster randomized trials: a review and comparison.
Review in International journal of epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Efficacy and safety of eltrombopag in combination with cyclosporine A for the treatment of adult refractory primary immune thrombocytopenia: a phase II, multicenter, single-arm, prospective study.Clinical and experimental medicine · 2026Trial
- Intravesical Interferon Therapy vs Hyaluronic Acid for Pain Among Female Individuals With Interstitial Cystitis: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Does it decay? Obtaining decaying correlation parameter values from previously analysed cluster randomised trials.Statistical methods in medical research · 2023Trial
- The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design.JMIR research protocols · 2026Article
- Evaluation of injury prevention interventions using the stepped wedge cluster randomised trial design: key considerations.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2026Article
- The design of embedded pragmatic clinical trials: methodological developments and statistical lessons learned from the first cycle of the NIA IMPACT collaboratory.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- A tutorial on conducting sample size and power calculations for detecting treatment effect heterogeneity in cluster randomized trials with linear mixed models.International journal of epidemiology · 2026Article
- Analysis of Stepped-Wedge Cluster Randomized Trials: A Tutorial Using Marginal Models.Statistics in medicine · 2026Article
- Sample size requirements and intra-cluster correlations for stepped wedge cluster randomised trials in intensive care medicine: A practical guide.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- Design and analysis of individually randomized multiple baseline factorial trials.Behavior research methods · 2026Article
- What scientific inferences can be made with randomized implementation rollout trials.Implementation science : IS · 2025Article
- Selecting the optimal longitudinal cluster randomized design with a continuous outcome: Parallel-arm, crossover, or stepped-wedge.Statistical methods in medical research · 2025Article
- Designing Stepped Wedge Cluster Randomized Trials With a Baseline Measurement of the Outcome.Statistics in medicine · 2025Article
- Grand rounds in methodology: improving the design of staggered implementation cluster randomised trials.BMJ quality & safety · 2025Article
- What Is a Stepped-Wedge Cluster Randomized Trial?JAMA internal medicine · 2025Article
- Power analysis for concurrent balanced or imbalanced multiple-intervention stepped wedge design: a simulation-based approach.BMC medical research methodology · 2025Article
- Power calculation for cross-sectional stepped wedge cluster randomized trials with a time-to-event endpoint.Biometrics · 2025Article
- Serosurvey ofPathogens (Basel, Switzerland) · 2025Article
- Bayesian Analysis of Time-To-Event Data in a Cluster-Randomized Trial: Major Outcomes With Personalized Dialysate TEMPerature (MyTEMP) Trial.Canadian journal of kidney health and disease · 2025Article
- How Do Researchers Identify and Recruit Dementia Caregivers? A Scoping Review.The Gerontologist · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Recent years have seen a surge of interest in stepped-wedge cluster randomized trials (SW-CRTs). SW-CRTs include several design variations and methodology is rapidly developing. Accordingly, a variety of power and sample size calculation software for SW-CRTs has been developed. However, each calculator may support only a selected set of design features and may not be appropriate for all scenarios. Currently, there is no resource to assist researchers in selecting the most appropriate calculator for planning their trials. In this paper, we review and classify 18 existing calculators that can be implemented in major platforms, such as R, SAS, Stata, Microsoft Excel, PASS and nQuery. After reviewing the main sample size considerations for SW-CRTs, we summarize the features supported by the available calculators, including the types of designs, outcomes, correlation structures and treatment effects; whether incomplete designs, cluster-size variation or secular trends are accommodated; and the analytical approach used. We then discuss in more detail four main calculators and identify their strengths and limitations. We illustrate how to use these four calculators to compute power for two real SW-CRTs with a continuous and binary outcome and compare the results. We show that the choice of calculator can make a substantial difference in the calculated power and explain these differences. Finally, we make recommendations for implementing sample size or power calculations using the available calculators. An R Shiny app is available for users to select the calculator that meets their requirements (https://douyang.shinyapps.io/swcrtcalculator/).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.