Evidence map›Paper›PMID 35679495›Full record

ArticleThe western journal of emergency medicine2022

Bamlanivimab Reduces ED Returns and Hospitalizations and May Reduce COVID-19 Burden on Low-resource Border Hospitals.

Faith C Quenzer, Andrew T Lafree, Londyn Grey, Sukhdeep Singh, Cameron Smyers, Bruce Balog, Henry Montilla Guedez, Kaitlin McIntyre, Sharon Wulfovich, Juli Ramirez and 2 more

Open access · goldAbstract readClinical Study
In one paragraph

Article in The western journal of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Faith C QuenzerSan Diego State University School of Public Health, San Diego, California.
Andrew T LafreeUniversity of California - San Diego, School of Medicine, Department of Emergency Medicine, San Diego, California.
Londyn GreyLouisiana State University Health Sciences Center, School of Medicine, Shreveport, Louisiana.
Sukhdeep SinghUniversity of California - San Diego, School of Medicine, Department of Emergency Medicine, San Diego, California.
Cameron SmyersUniversity of California - San Diego, School of Medicine, Department of Emergency Medicine, San Diego, California.
Bruce BalogEl Centro Regional Medical Center, Department of Emergency Medicine, El Centro, California.
Henry Montilla GuedezUniversity of California - San Diego, School of Medicine, Department of Emergency Medicine, San Diego, California.
Kaitlin McIntyreUniversity of California - San Diego, School of Medicine, Department of Emergency Medicine, San Diego, California.
Sharon WulfovichUniversity of California - San Diego, School of Medicine, Department of Emergency Medicine, San Diego, California.
Juli RamirezEl Centro Regional Medical Center, Department of Emergency Medicine, El Centro, California.
Talia SaikhonEl Centro Regional Medical Center, Department of Emergency Medicine, El Centro, California.
Christian TomaszewskiUniversity of California - San Diego, School of Medicine, Department of Emergency Medicine, San Diego, California.
San Diego State University · USLouisiana State University · USRegional Medical Center · USUniversity of California, San Diego · USLouisiana State University Health Sciences Center Shreveport · USLouisiana State University in Shreveport · USUniversity of San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo evaluate the effectiveness of bamlanivimab at reducing return emergency department (ED) visits in primarily Latinx/Hispanic patients with mild or moderate coronavirus disease 2019 (COVID-19). Secondary aims were to evaluate the prevention of subsequent hospitalizations and deaths in a resource-limited United States (U.S.)-Mexico border hospital.

methodsWe conducted a retrospective, open-label interventional study on 270 eligible adult patients diagnosed with mild-moderate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who met criteria for receiving bamlanivimab from November 1, 2020 to January 31, 2021. The main outcomes of 14-day return visits to the ED and hospitalizations due to COVID-19 were compared between two groups - those who received bamlanivimab (exposed group) and those who did not receive bamlanivimab (unexposed group). Outcomes were analyzed through chi-square tests followed by multivariate regression modeling to adjust for patient demographics, characteristics, and comorbidities.

resultsThere were 136 COVID-19 patients who received bamlanivimab in the ED prior to discharge and an unexposed group of 134 COVID-19 patients who were evaluated and discharged from the ED without receiving bamlanivimab. Overall, mean age was 61.7 (S.D. +/-13.9) years, mean body mass index (BMI) 31.0 (S.D. +/-6.6) kg/m

conclusionBamlanivimab infusions for high-risk COVID-19 patients in the ED substantially reduced the risk of return visits to the ED and hospitalizations in our primarily Latinx/Hispanic population. Monoclonal antibody infusions may help reduce hospital utilization during COVID-19 surges at U.S.-Mexico border hospitals.

Indexed as

COVID-19 Drug TreatmentAdultAntibodies, Monoclonal, HumanizedAntibodies, NeutralizingEmergency Service, HospitalFemaleHospitalizationHospitalsHumansMaleMiddle AgedRetrospective StudiesSARS-CoV-2United StatesAntibodies, Monoclonal, HumanizedAntibodies, Neutralizingbamlanivimab

Identifiers

PMID35679495
PMCPMC9183783
OpenAlexW4281392029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.