Evidence map›Paper›PMID 35679493›Full record

ArticleThe western journal of emergency medicine2022

Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department.

Rebecca Hluhanich, James S Ford, Devin Bruce, Tasleem Chechi, Stephanie Voong, Souvik Sarkar, Patricia Poole, Nam Tran, Larissa May

Open access · goldAbstract read
In one paragraph

Article in The western journal of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rebecca HluhanichUC Davis Health, Hepatology and Infectious Diseases Clinical Pharmacy, Sacramento, California.
James S FordUC Davis Health, Department of Emergency Medicine, Sacramento, California.
Devin BruceUC Davis Health, Department of Emergency Medicine, Sacramento, California.
Tasleem ChechiUC Davis Health, Department of Emergency Medicine, Sacramento, California.
Stephanie VoongUC Davis Health, Department of Emergency Medicine, Sacramento, California.
Souvik SarkarUC Davis Health, Department of Internal Medicine, Division of Gastroenterology, Sacramento, California.
Patricia PooleUC Davis Health, Department of Pharmacy, Sacramento, California.
Nam TranUC Davis Health, Department of Pathology and Laboratory Medicine, Sacramento, California.
Larissa MayUC Davis Health, Department of Emergency Medicine, Sacramento, California.
UC Davis Health System · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNew evidence suggests that emergency department (ED)-based infectious diseases screening programs have utility. We aimed to compare clinic-based and ED-based hepatitis C virus (HCV) screening programs within a single health system, to identify key differences in HCV antibody (Ab) positivity and chronic HCV, as well as population demographics.

methodsIn the clinic-based program, adults in the birth cohort (born 1945-1965) were screened for HCV. In the ED-based program, non-targeted HCV screening of all adults was conducted. We included patients screened between June 2019-June 2020. Patients were screened for anti-HCV Ab, and positive results were followed by HCV viral load (VL) testing. Our primary outcomes were seroprevalence of HCV Ab and HCV VL.

resultsThere were 1,296 and 12,778 patients screened for HCV in the clinics and the ED, respectively. In the clinic setting, 13 patients (1%) screened positive for HCV Ab and nine (69%) completed VL testing, which was positive in one patient (11%). In the ED, 1,053 patients (8%) screened positive for HCV Ab and 847 (80%) underwent reflex VL testing, which was positive in 381 patients (45%). In an ED birth cohort sub-analysis, Hepatitis C virus Ab seroprevalence was 15% (675/4521).

conclusionIn this study of patients in a single healthcare system, ED-based HCV screening was higher yield than clinic-based screening.

Indexed as

HepacivirusHepatitis CAdultEmergency Service, HospitalHepatitis C AntibodiesHumansMass ScreeningSeroepidemiologic StudiesHepatitis C Antibodies

Identifiers

PMID35679493
PMCPMC9183782
OpenAlexW4282942451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.