ArticleProceedings of the National Academy of Sciences of the United States of America2022
Terminating spiral waves with a single designed stimulus: Teleportation as the mechanism for defibrillation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Optimal control of spiral waves in heterogeneous excitable media: non-monotonic efficacy of localized optogenetic inhibition.Journal of the Royal Society, Interface · 2026Article
- Deep Learning for analyzing chaotic dynamics in biological time series: Insights from frog heart signals.Neurocomputing · 2026Article
- Exploring wave propagation dynamics in heterogeneous excitable media: effects of intermittent cellular inactivation.Frontiers in physiology · 2026Article
- A topological hypothesis for atrial fibrilllation, atrial flutter and focal atrial tachycardia: comparison and contrast with Kosterlitz-Thouless physics.Frontiers in network physiology · 2025Article
- Termination of figure-of-eight reentry via resonant feedback pacing.Frontiers in network physiology · 2025Article
- Reentry-driven model of atrial fibrillation is maintained by paired reentries and terminated by strategic pairwise virtual ablation.Frontiers in physiology · 2025Article
- Fast interactive simulations of cardiac electrical activity in anatomically accurate heart structures by compressing sparse uniform cartesian grids.Computer methods and programs in biomedicine · 2024Article
- Morphogenic Modeling of Corrosion Reveals Complex Effects of Intermetallic Particles.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Experimental studies of spiral wave teleportation in a light sensitive Belousov-Zhabotinsky system.Chaos (Woodbury, N.Y.) · 2024Article
- Chaos control in cardiac dynamics: terminating chaotic states with local minima pacing.Frontiers in network physiology · 2024Article
- Pattern selection by material aging: Modeling chemical gardens in two and three dimensions.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Fiber Organization Has Little Effect on Electrical Activation Patterns During Focal Arrhythmias in the Left Atrium.IEEE transactions on bio-medical engineering · 2023Article
- Article
- Optimising low-energy defibrillation in 2D cardiac tissue with a genetic algorithm.Frontiers in network physiology · 2023Article
- A smoothed boundary bidomain model for cardiac simulations in anatomically detailed geometries.PloS one · 2023Article
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Authors and funding
3 authors.
Funding
Abstract
We identify and demonstrate a universal mechanism for terminating spiral waves in excitable media using an established topological framework. This mechanism dictates whether high- or low-energy defibrillation shocks succeed or fail. Furthermore, this mechanism allows for the design of a single minimal stimulus capable of defibrillating, at any time, turbulent states driven by multiple spiral waves. We demonstrate this method in a variety of computational models of cardiac tissue ranging from simple to detailed human models. The theory described here shows how this mechanism underlies all successful defibrillation and can be used to further develop existing and future low-energy defibrillation strategies.
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