Evidence map›Paper›PMID 35679302›Full record

ArticleGenome biology and evolution2022

Population Genomics of Variegated Toad-Headed Lizard Phrynocephalus versicolor and Its Adaptation to the Colorful Sand of the Gobi Desert.

Yuanting Jin, Diana Aguilar-Gómez, Débora Y C Brandt, Tyler A Square, Jiasheng Li, Zhengxia Liu, Tao Wang, Peter H Sudmant, Craig T Miller, Rasmus Nielsen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genome biology and evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Long-term evolutionary persistence of a cryptic color polymorphism in frogs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Inferring Balancing Selection From Genome-Scale Data.Genome biology and evolution · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuanting JinCollege of Life Sciences, China Jiliang University, Hangzhou 310018, Zhejiang, China.
Diana Aguilar-GómezCenter for Computational Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0001-5930-3936
Débora Y C BrandtDepartment of Integrative Biology, University of California Berkeley, Berkeley, CA, USA.
Tyler A SquareDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Jiasheng LiCollege of Life Sciences, China Jiliang University, Hangzhou 310018, Zhejiang, China.
Zhengxia LiuCollege of Life Sciences, China Jiliang University, Hangzhou 310018, Zhejiang, China.
Tao WangCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Peter H SudmantCenter for Computational Biology, University of California Berkeley, Berkeley, CA, USA.
Craig T MillerDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Rasmus NielsenCenter for Computational Biology, University of California Berkeley, Berkeley, CA, USA.ORCID 0000-0003-0513-6591

Funding

The evolution and diversity of mutation, molecular fidelity, and genome structureR35GM142916 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Peter Heshedahl Sudmant · 2021 to 2026
$2.5M
NIGMS NIH HHS R35 GM142916
6 · The paper itself

Abstract

The variegated toad-headed agama, Phrynocephalus versicolor, lives in the arid landscape of the Chinese Gobi Desert. We analyzed populations from three different locations which vary in substrate color and altitude: Heishankou (HSK), Guazhou County (GZ), and Ejin Banner (EJN). The substrate color is either light-yellow (GZ-y), yellow (EJN-y), or black (HSK-b); the corresponding lizard population colors largely match their substrate in the degree of melanism. We assembled the P. versicolor genome and sequenced over 90 individuals from the three different populations. Genetic divergence between populations corresponds to their geographic distribution. We inferred the genetic relationships among these populations and used selection scans and differential expression to identify genes that show signatures of selection. Slc2a11 and akap12, among other genes, are highly differentiated and may be responsible for pigment adaptation to substrate color in P. versicolor.

Indexed as

Genome, MitochondrialLizardsAnimalsHumansMetagenomicsRNA, TransferSandRNA, TransferSandgeneticslizardmelanismpigmentation

Identifiers

PMID35679302
PMCPMC9260186

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.