Evidence map›Paper›PMID 35678766›Full record

ArticleAnnals of the New York Academy of Sciences2022

Role of hair follicles in the pathogenesis of arsenical-induced cutaneous damage.

Ritesh K Srivastava, Yong Wang, Jasim Khan, Suhail Muzaffar, Madison B Lee, Zhiping Weng, Claire Croutch, Anupam Agarwal, Jessy Deshane, Mohammad Athar

Open access · greenAbstract read
In one paragraph

Article in Annals of the New York Academy of Sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  9. Effects ofInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ritesh K SrivastavaUAB Research Center of Excellence in Arsenicals, Department of Dermatology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Yong WangDivision of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jasim KhanUAB Research Center of Excellence in Arsenicals, Department of Dermatology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Suhail MuzaffarUAB Research Center of Excellence in Arsenicals, Department of Dermatology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Madison B LeeUAB Research Center of Excellence in Arsenicals, Department of Dermatology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Zhiping WengUAB Research Center of Excellence in Arsenicals, Department of Dermatology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Claire CroutchMRIGlobal Medical Countermeasures Division, Kansas City, Missouri, USA.
Anupam AgarwalDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jessy DeshaneDivision of Pulmonary Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Mohammad AtharUAB Research Center of Excellence in Arsenicals, Department of Dermatology, School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
University of Alabama at Birmingham · USBirmingham VA Medical Center · USMRIGlobal · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
UAB Research Center of Excellence in ArsenicalsU54ES030246 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2018 to 2022
$19.0M
Project 5 Nano-micro Hybrid Fibrous Materials for Containment Removal and Site RemediationP42ES027723 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUNGU, CLAUDIU T · 2020 to 2024
$6.7M
Optimization of Novel Molecular Target-based Drugs for Arsenical Skin InjuryU01AR078544 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ATHAR, MOHAMMAD · 2020 to 2024
$3.9M
NCI NIH HHS P30 CA013148NIAMS NIH HHS U01 AR078544NIEHS NIH HHS P42 ES027723NIEHS NIH HHS U54 ES030246
6 · The paper itself

Abstract

Arsenical vesicants cause skin inflammation, blistering, and pain. The lack of appropriate animal models causes difficulty in defining their molecular pathogenesis. Here, Ptch1

Indexed as

ArsenicalsChemical Warfare AgentsAnimalsChemokinesCytokinesHair FollicleInflammationIrritantsMiceMice, HairlessMice, Inbred C57BLReactive Oxygen SpeciesSkinArsenicalsChemical Warfare AgentsChemokinesCytokinesIrritantslewisiteoxophenylarsineReactive Oxygen Speciesanimal modelarsenicalshair follicleskin injuryvesicants

Identifiers

PMID35678766
PMCPMC9531897
OpenAlexW4281629302

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.