Evidence map›Paper›PMID 35678757›Full record

ArticleMolecular microbiology2022

The transmembrane α-helix of LptC participates in LPS extraction by the LptB

Andrew Wilson, Natividad Ruiz

Open access · greenAbstract read
In one paragraph

Article in Molecular microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The LptC transmembrane helix undergoes a rigid body movement upon LptBProtein science : a publication of the Protein Society · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Residues within the LptC transmembrane helix are critical for Escherichia coli LptBProtein science : a publication of the Protein Society · 2024
    Article
  10. Article
  11. Article
  12. ABC Transporters in Bacterial Nanomachineries.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew WilsonDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.
Natividad RuizDepartment of Microbiology, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0002-6369-2206
The Ohio State University · US

Funding

Envelope Biogenesis in Gram-negative BacteriaR01GM100951 · NIGMS · OHIO STATE UNIVERSITY · PI RUIZ, NATIVIDAD · 2012 to 2023
$3.7M
Cellular, molecular, and biochemical sciences training grantT32GM086252 · NIGMS · OHIO STATE UNIVERSITY · PI JACKMAN, JANE ELIZABETH, MUSIER-FORSYTH, KARIN M · 2011 to 2020
$2.0M
NIGMS NIH HHS R01 GM100951NIGMS NIH HHS T32 GM086252
6 · The paper itself

Abstract

Lipopolysaccharide (LPS) is an essential component of the outer membrane of most Gram-negative bacteria that provides resistance to various toxic compounds and antibiotics. Newly synthesized LPS is extracted from the inner membrane by the ATP-binding cassette (ABC) transporter LptB

Indexed as

Escherichia coliEscherichia coli ProteinsLipopolysaccharidesAdenosine TriphosphatasesATP-Binding Cassette TransportersBiological TransportMembrane ProteinsProtein Conformation, alpha-HelicalAdenosine TriphosphatasesATP-Binding Cassette TransportersEscherichia coli ProteinsLipopolysaccharidesLptB protein, E coliLptC protein, E coliMembrane ProteinsABC transporterglycolipidlipid transportmembrane biogenesistransenvelope

Identifiers

PMID35678757
PMCPMC9544173
OpenAlexW4281777810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.