Evidence map›Paper›PMID 35678613›Full record

ArticleRNA biology2022

The sRNA NsiR4 fine-tunes arginine synthesis in the cyanobacterium

Paul Bolay, Luisa Hemm, Francisco J Florencio, Wolfgang R Hess, M Isabel Muro-Pastor, Stephan Klähn

Open access · goldAbstract read
In one paragraph

Article in RNA biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Paul BolayDepartment of Solar Materials, Helmholtz Centre for Environmental Research, Leipzig, Germany.ORCID 0000-0001-5047-8596
Luisa HemmGenetics and Experimental Bioinformatics, Faculty of Biology, University of Freiburg, Freiburg, Germany.
Francisco J Florenciode Sevilla, Instituto de Bioquímica Vegetal Y FotosíntesisCSIC-Universidad, Sevilla, Spain.ORCID 0000-0002-2068-7861
Wolfgang R HessGenetics and Experimental Bioinformatics, Faculty of Biology, University of Freiburg, Freiburg, Germany.ORCID 0000-0002-5340-3423
M Isabel Muro-Pastorde Sevilla, Instituto de Bioquímica Vegetal Y FotosíntesisCSIC-Universidad, Sevilla, Spain.
Stephan KlähnDepartment of Solar Materials, Helmholtz Centre for Environmental Research, Leipzig, Germany.ORCID 0000-0002-2933-486X
Helmholtz Centre for Environmental Research · DEInstituto de Bioquímica Vegetal y Fotosíntesis · ESUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the only oxygenic phototrophs among prokaryotes, cyanobacteria employ intricate mechanisms to regulate common metabolic pathways. These mechanisms include small protein inhibitors exerting their function by protein-protein interaction with key metabolic enzymes and regulatory small RNAs (sRNAs). Here we show that the sRNA NsiR4, which is highly expressed under nitrogen limiting conditions, interacts with the mRNA of the recently described small protein PirA in the model strain

Indexed as

Ammonium CompoundsSynechocystisArginineBacterial ProteinsGene Expression Regulation, BacterialNitrogenAmmonium CompoundsArginineBacterial ProteinsNitrogenarginine metabolismCyanobacterianitrogen assimilationposttranscriptional regulationRNA regulatorsRNA

Identifiers

PMID35678613
PMCPMC9196836
OpenAlexW4281681320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.