ReviewJournal of the American Medical Informatics Association : JAMIA2022
Standardizing, harmonizing, and protecting data collection to broaden the impact of COVID-19 research: the rapid acceleration of diagnostics-underserved populations (RADx-UP) initiative.
Review in Journal of the American Medical Informatics Association : JAMIA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Reporting practices of baseline and surgical variables in spinal cavernous malformation surgery: a systematic review.Neurosurgical review · 2026Pooled it
- Social determinants of health and COVID-19 vaccination: An individual participant data meta-analysis of adult Latino participants.Preventive medicine · 2025Pooled it
- REPRESENT recommendations: improving inclusion and trust in cancer early detection research.British journal of cancer · 2023Pooled it
- Chronic Health Conditions and Uptake of COVID-19 Testing and Vaccination Among Native Americans in Oklahoma in the RADx-UP Consortium.Journal of racial and ethnic health disparities · 2026Article
- Integrating real-world data with gold-standard longitudinal clinical and genomic data to advance precision medicine for the Alzheimer's Disease Research Center Program and beyond: a proof-of-concept data platform.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Low Risk, High Stakes: Factors Associated with Low COVID-19 Risk Perception Among Black Chicago Residents.Journal of racial and ethnic health disparities · 2025Article
- Chronic conditions, disability, and COVID-19 testing and vaccination: A national Rapid Acceleration of Diagnostics-Underserved Populations analysis.Annals of epidemiology · 2025Article
- The relationship between living in poverty and youth COVID-19 testing in underserved populations.Annals of epidemiology · 2025Article
- A community-engaged approach to developing common data elements: a case study from the RADx-UP Long COVID common data elements Task Force.JAMIA open · 2025Article
- Lessons from community during COVID-19: understanding needs and preferences for the development of a disease prevention and health promotion initiative.Discover public health · 2025Article
- A protocol for tracking scholarly output to evaluate the impact of the RADx-UP program on community-engaged COVID-19 research.Journal of clinical and translational science · 2025Article
- Integrating community perspectives to improve survey completion rates in public health research by refining controversial survey elements.Journal of clinical and translational science · 2025Article
- Article
- Factors Associated with COVID-19 Vaccination Uptake in Great Plains American Indian Communities.Journal of racial and ethnic health disparities · 2024Article
- Community-Engaged Research: COVID-19 Testing, Infection, and Vaccination among Underserved Minority Communities in Miami, Florida.Vaccines · 2024Article
- Drug use and COVID-19 testing, vaccination, and infection among underserved, minority communities in Miami, Florida.PloS one · 2024Article
- COVID-19 Testing Factors Among Great Plains American Indians.Journal of racial and ethnic health disparities · 2023Article
- Examining COVID-19 testing and vaccination behaviors by heritage and linguistic preferences among Hispanic, Latino, or Spanish RADx-UP participants.Preventive medicine reports · 2023Article
- Article
- Continuing the journey toward semantic interoperability in clinical care and biomedical and health research.Journal of the American Medical Informatics Association : JAMIA · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe Rapid Acceleration of Diagnostics-Underserved Populations (RADx-UP) program is a consortium of community-engaged research projects with the goal of increasing access to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) tests in underserved populations. To accelerate clinical research, common data elements (CDEs) were selected and refined to standardize data collection and enhance cross-consortium analysis. MATERIALS AND
methodsThe RADx-UP consortium began with more than 700 CDEs from the National Institutes of Health (NIH) CDE Repository, Disaster Research Response (DR2) guidelines, and the PHENotypes and eXposures (PhenX) Toolkit. Following a review of initial CDEs, we made selections and further refinements through an iterative process that included live forums, consultations, and surveys completed by the first 69 RADx-UP projects.
resultsFollowing a multistep CDE development process, we decreased the number of CDEs, modified the question types, and changed the CDE wording. Most research projects were willing to collect and share demographic NIH Tier 1 CDEs, with the top exception reason being a lack of CDE applicability to the project. The NIH RADx-UP Tier 1 CDE with the lowest frequency of collection and sharing was sexual orientation. DISCUSSION: We engaged a wide range of projects and solicited bidirectional input to create CDEs. These RADx-UP CDEs could serve as the foundation for a patient-centered informatics architecture allowing the integration of disease-specific databases to support hypothesis-driven clinical research in underserved populations.
conclusionA community-engaged approach using bidirectional feedback can lead to the better development and implementation of CDEs in underserved populations during public health emergencies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.