Evidence map›Paper›PMID 35678178›Full record

ArticleDevelopment and psychopathology2023

Early-life adversity is associated with poor iron status in infancy.

Brie M Reid, Patricia East, Estela Blanco, Jenalee R Doom, Raquel A Burrows, Paulina Correa-Burrows, Betsy Lozoff, Sheila Gahagan

Abstract read
In one paragraph

Article in Development and psychopathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Cortisol Stress Response is Associated with Iron Status in Pregnancy.medRxiv : the preprint server for health sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Brie M ReidDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, RI, USA.ORCID 0000-0003-0056-5995
Patricia EastDepartment of Pediatrics, University of California, San Diego, CA, USA.
Estela BlancoDepartment of Public Health, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Jenalee R DoomDepartment of Psychology, University of Denver, Denver, CO, USA.ORCID 0000-0003-2857-0817
Raquel A BurrowsInstitute of Nutrition and Food Technology, University of Chile, Santiago, Chile.
Paulina Correa-BurrowsInstitute of Nutrition and Food Technology, University of Chile, Santiago, Chile.
Betsy LozoffDepartment of Pediatrics, University of Michigan, Ann Arbor, MI, USA.
Sheila GahaganDepartment of Pediatrics, University of California, San Diego, CA, USA.

Funding

NEUROMATURATION DELAYS IN IRON DEFICIENT ANEMIC INFANTSR01HD033487 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA, LOZOFF, BETSY · 1997 to 2016
$8.8M
Biopsychosocial Determinants of Adolescent Obesity/Cardiovascular RiskR01HL088530 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA · 2008 to 2017
$5.0M
Research Training in Childhood Stress, Trauma, and ResilienceT32HD101392 · NICHD · MIRIAM HOSPITAL · PI PARADE, STEPHANIE HART, STROUD, LAURA R · 2020 to 2024
$1.7M
Testing cortisol dysregulation as a mediator between early stress and adolescent cardiovascular healthK01HL143159 · NHLBI · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI DOOM, JENALEE RAE · 2019 to 2023
$788k
Long-Term Cognitive and Behavioral Effects of Early-Life Iron Deficiency and High-Iron SupplementationR03HD097295 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI EAST, PATRICIA L · 2019 to 2020
$126k
NHLBI NIH HHS K01 HL143159NHLBI NIH HHS R01 HL088530NICHD NIH HHS R01 HD033487NICHD NIH HHS R03 HD097295NICHD NIH HHS T32 HD101392NIH HHS R01 HD14122NIH HHS R01 HD33487NIH HHS R03 HD097295NIH HHS T32 HD101392
6 · The paper itself

Abstract

Exposure to early-life adversity (ELA) and iron deficiency early in life are known risk factors for suboptimal brain and socioemotional development. Iron deficiency may arise from and co-occur with ELA, which could negatively affect development. In the present study, we investigated whether ELA is associated with iron deficiency in infants receiving no iron supplementation. This study is a secondary analysis of extant data collected in the 1990s; participants were healthy infants from working-class communities in Santiago, Chile (

Indexed as

Adverse Childhood ExperiencesIron DeficienciesAnimalsChildChild DevelopmentFemaleHumansInfantIronMalePregnancyRisk FactorsIronearly-life adversityinfancyiron deficiencynutritionstress

Identifiers

PMID35678178
PMCPMC9732147

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.