ArticleHospital pediatrics2022
Feasibility of a Centralized, Pharmacy-Led Penicillin Allergy Delabeling Program.
Article in Hospital pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Self-Reported Penicillin Allergy, Alternative Antibiotics, and Implant Outcomes: A Retrospective Study.Clinical implant dentistry and related research · 2026Article
- Deficiencies in the Assessment of Penicillin Allergy in Hospitalized Children in Hawai'i, 2021-2023.Hawai'i journal of health & social welfare · 2026Article
- Article
- Using the Electronic Health Record to Facilitate Drug Allergy Delabeling.Current allergy and asthma reports · 2025Review
- A Rash Decision: Implementing an EHR-Integrated Penicillin Allergy Delabeling Protocol without Adequate Clinician Support.Applied clinical informatics · 2025Article
- Beta-Lactam Allergy De-labeling in a Pediatric Hospital.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Barriers to penicillin allergy de-labeling in the inpatient and outpatient settings: a qualitative study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023Article
- Penicillin allergy delabeling: Opportunities for implementation and dissemination.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023Review
- Parental Perceptions of Penicillin Allergy Risk Stratification and Delabeling.Hospital pediatrics · 2023Article
- Assessment of a Stepwise Intervention to Improve Nurse-administered Penicillin Allergy Screening and De-labeling in Pediatric Inpatients.Pediatric quality & safetyArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPenicillin allergy labels are often inaccurate in children and removing unnecessary labels results in improved outcomes and lower health care costs. Although the hospital setting is a frequent point of contact for children, strategies to evaluate penicillin allergies in the hospital are lacking.
methodsWe performed a prospective pilot study to determine the feasibility of a centralized, pharmacy-led approach to penicillin allergy evaluation. Children with a reported history of penicillin allergy admitted to our children's hospital were risk-stratified and those stratified as low-risk underwent a single-dose oral challenge by a central pharmacist, regardless of the need for antibiotics. After the completion of each patient's delabeling process, surveys were distributed to health care personnel involved in the patient's care to collect perceptions on the acceptability, appropriateness, and feasibility of this intervention. Measures were scored by using a 5-point Likert scale.
resultsOf the 23 patients who screened as low-risk, 20 underwent a penicillin allergy evaluation and an oral challenge. Of these, the penicillin allergy label was removed in 19 (95%) patients (Fig 1). The median age was 7 years (range 11 months-18 years). Participants rated the risk stratification and delabeling favorably overall, with high ratings on all 3 implementation measures: acceptability (mean 4.55, ± standard deviation [STD] 0.65), appropriateness (mean 4.58, STD ± 0.6), and feasibility (mean 4.51, STD ± 0.73). Measures of acceptability, appropriateness, and feasibility remained high when stratified by health care worker type and provider type.
conclusionsOur findings provide support for systemic implementation of penicillin allergy delabeling strategies in hospitalized children.
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