ArticleJournal of stroke2022
Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality.
Erratum issued Registry-linked trialOpen access · diamondAbstract read
In one paragraph
Article in Journal of stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04934020 (Global Impact of the COVID 19 Pandemic on Stroke Care), which is not on this map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Global Impact of the COVID 19 Pandemic on Stroke Care: 1-year Follow-up Study
Who cites it
19 citing papers in PubMed, 51 citations in OpenAlex.
- Engineering neurovascular thrombosis: Light-based bioprinting for patient-specific modeling and women's cerebrovascular health.Science advances · 2026Review
- Clinical characteristics and outcomes of SARS-CoV-2-associated stroke: a large multicenter national cohort study.Einstein (Sao Paulo, Brazil) · 2026Article
- A deep learning based radiomics model for differentiating intraparenchymal hematoma induced by cerebral venous thrombosis.Scientific reports · 2025Article
- Exploring the role of mitochondrial dysfunction and aging in COVID-19-Related neurological complications.Molecular biology reports · 2025Review
- International practice patterns and perspectives on endovascular therapy for the treatment of cerebral venous thrombosis.International journal of stroke : official journal of the International Stroke Society · 2025Article
- The Impact of COVID-19 on Admissions and In-hospital Mortality of Patients With Stroke in Korea: An Interrupted Time Series Analysis.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025Article
- Platelet count and sleep quality in immune thrombocytopenia: correlation with 5-hydroxytryptamine and therapeutic implications of platelet-5-HT-melatonin axis dysregulation.Frontiers in neurology · 2025Article
- Genetic Testing Among Breast Cancer Patients in the Eastern Region of Saudi Arabia: Single-Center Experience.Journal of epidemiology and global health · 2024Article
- Reducing the global burden of cerebral venous thrombosis: An international research agenda.International journal of stroke : official journal of the International Stroke Society · 2024Review
- Stroke in Asia.Cerebrovascular diseases extra · 2024Review
- Epidemiology, pathogenesis, and management of Coronavirus disease 2019-associated stroke.Frontiers of medicine · 2023Review
- Stroke metrics during the first year of the COVID-19 pandemic, a tale of two comprehensive stroke centers.Scientific reports · 2023Article
- Delayed Diagnosis in Cerebral Venous Thrombosis: Associated Factors and Clinical Outcomes.Journal of the American Heart Association · 2023Article
- Cerebrovascular Disease in COVID-19.Viruses · 2023Review
- Patterns of acute ischemic stroke and intracranial hemorrhage in patients with COVID-19 : Results of a retrospective multicenter neuroimaging-based study from three central European countries.Journal of neurology · 2023Article
- Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up.Neurology · 2023Observational
- Observational
- The Impact of COVID-19 Pandemic Lockdown on Emergency Department Visits in a Tertiary Hospital.Risk management and healthcare policy · 2023Article
- Outcome Prediction in Cerebral Venous Thrombosis: The IN-REvASC Score.Journal of stroke · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
282 authors at 16 institutions in 10 countries.
Thanh N NguyenDepartment of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Muhammad M QureshiDepartment of Radiology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Piers KleinDepartment of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Hiroshi YamagamiDepartment of Stroke Neurology, National Hospital Organization, Osaka National Hospital, Osaka, Japan.
Mohamad AbdalkaderDepartment of Radiology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Robert MikulikDepartment of Neurology, International Clinical Research Center, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Anvitha SathyaDepartment of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Ossama Yassin MansourDepartment of Neurology, Alexandria University, Alexandria, Egypt.
Anna Czlonkowska2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.
Hannah LoDepartment of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Thalia S FieldDivision of Neurology, Dept. Medicine, University of British Columbia, Vancouver, BC, Canada.
Andreas CharidimouDepartment of Neurology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Soma BanerjeeDepartment of Stroke Medicine, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.
Shadi YaghiDepartment of Neurology, Rhode Island Hospital, Brown University, Providence, RI, USA.
James E SieglerDepartment of Neurology, Cooper University, Camden, NJ, USA.
Petra SedovaDepartment of Neurology, International Clinical Research Center, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Joseph KwanDepartment of Stroke Medicine, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.
Diana Aguiar de SousaDepartment of Neurology, Hospital de Santa Maria, North Lisbon University Hospital Center (CHULN), Lisbon, Portugal.
Jelle DemeestereNeurology Department, Leuven University Hospital, Leuven, Belgium.
Violiza InoaDepartment of Neurology, University of Tennessee Health Science Center, Memphis, TN, USA.
Setareh Salehi OmranDepartment of Neurology, University of Colorado School of Medicine, Aurora, CO, USA.
Liqun ZhangDepartment of Neurology St George's University Hospital, London, UK.
Patrik MichelDepartment of Neurosciences, Lausanne University Hospital, Lausanne, Switzerland.
Davide StramboDepartment of Neurosciences, Lausanne University Hospital, Lausanne, Switzerland.
João Pedro MartoDepartment of Neurology, Egas Moniz Hospital, West Lisbon Hospital Center (CHLO), Lisbon, Portugal.
Raul G NogueiraDepartment of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
SVIN COVID-19 Global COVID Stroke Registry
Espen Saxhaug KristoffersenDepartment of Neurology, Akershus University Hospital, University of Oslo, Lørenskog, Norway.
Georgios TsivgoulisSecond Department of Neurology, "Attikon" University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Virginia Pujol LereisDivision de Neurologia Vascular, Departmento de Neurologia, Institute for Neurological Research - FLENI, Buenos Aires, Argentina.
Alice MaRoyal North Shore Hospital, Sydney, Australia.
Christian EnzingerDepartment of Neurology, Medical University of Graz, Graz, Austria.
Thomas GattringerDepartment of Neurology and Division of Neuroradiology, Vascular and Interventional Radiology, Medical University of Graz, Graz, Austria.
Aminur RahmanDepartment of Neurology, Sir Salimullah Medical College, Mitford, Dhaka, Bangladesh.
Thomas BonnetHopital Erasme, Brussels, Belgium.
Noémie LigotHopital Erasme, Brussels, Belgium.
Sylvie De RaedtDepartment of Neurology, Universitair Ziekenhuis Brussel, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium.
Robin LemmensNeurology Department, Leuven University Hospital, Leuven, Belgium.
Peter VanackerDepartment of Neurology, University Hospitals Antwerp, Antwerp, Belgium.
Fenne VandervorstDepartment of Neurology, Universitair Ziekenhuis Brussel, Center for Neurosciences, Vrije Universiteit Brussel, Brussels, Belgium.
Adriana Bastos ConfortoHospital das Clínicas, São Paulo University, São Paulo , Brazil.
Raquel C T HidalgoDepartment of Neurology and Interventional Neuroradiology, Hospital de Base de São José do Rio Preto, São Paulo, Brazil.
Daissy Liliana Mora CuervoMoinhos de Vento Hospital, Brazil, Porto Alegre, Brazil.
Luciana de Oliveira NevesHospital São Carlos, Brazil, Fortaleza, Brazil.
Isabelle Lameirinhas da SilvaHospital das Clínicas, São Paulo University, São Paulo , Brazil.
Rodrigo Targa MartínsStroke Unit, Neurology, Nossa Senhora da Conceição Hospital, Porto Alegre, Brazil.
Letícia C RebelloHospital de Base do Distrito Federal, Brasilia, Brazil.
Igor Bessa SantiagoHospital São Carlos, Brazil, Fortaleza, Brazil.
Teodora SakelarovaSt. Anna University Hospital, Sofia, Bulgaria.
Rosen KalpachkiSt. Anna University Hospital, Sofia, Bulgaria.
Filip AlexievSt. Anna University Hospital, Sofia, Bulgaria.
Elena Adela CoraDepartment of Diagnostic Radiology, Halifax Infirmary, Dalhousie University, Halifax, Canada.
Michael E KellyRoyal University Hospital, Saskatoon, Canada.
Lissa PeelingRoyal University Hospital, Saskatoon, Canada.
Aleksandra PikulaToronto Western Hospital, University of Toronto, Toronto, Canada.
Hui-Sheng ChenDepartment of Neurology, General Hospital of Northern Theater Command, Shen Yang, China.
Yimin ChenDepartment of Neurology, Foshan Sanshui District People's Hospital, Foshan, China.
Shuiquan YangDepartment of Neurology, Foshan Sanshui District People's Hospital, Foshan, China.
Marina Roje BedekovicDepartment of Neurology, Sestre Milosrdnice University Hospital Center, Croatia, Zagreb, Croatia.
Martin ČabalDepartment of Neurology, Faculty Hospital Ostrava, Ostrava, Czech Republic.
Dusan TenoraDepartment of Neurology, Blansko Hospital, Czech Republic, Blansko, Czech Republic.
Petr FibrichOblastní nemocnice Trutnov a.s., Trutnov, Czech Republic.
Pavel DušekDepartment of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic.
Helena HlaváčováNeurology, Hospital Příbram, Příbram, Czech Republic.
Emanuela HrabanovskaUherskohradišťská Hospital, Uherské Hradiště, Czech Republic.
Lubomír JurákNeurocenter, Regional Hospital Liberec, Liberec, Czech Republic.
Jana KadlčíkováNeurology, Hospital Vyskov, Vyskov, Czech Republic.
Igor KarpowiczRegional Hospital Karlovy Vary, Karlovy Vary, Czech Republic.
Lukáš KlečkaMunicipal Hospital Ostrava, Ostrava, Czech Republic.
Martin KovářNa Homolce Hospital, Prague, Czech Republic.
Jiří NeumannDepartment of Neurology, Krajská zdravotní-Hospital Chomutov, Chomutov, Czech Republic.
Hana PalouškováKarvina Mining Hospital, Czech Republic, Karvina, Czech Republic.
Martin ReiserNeurology, České Budejovice Hospital, České Budějovice, Czech Republic.
Vladimir RohanDepartment of Neurology, University Hospital Plzen, Plzen, Czech Republic.
Libor ŠimůnekDepartment of Neurology, Comprehensive Stroke Center, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic.
Ondreij SkodaDepartment of Neurology, Hospital Jihlava, Jihlava, Czech Republic.
Miroslav ŠkorňaDepartment of Neurology, Masaryk University Faculty of Medicine, University Hospital Brno, Brno, Czech Republic.
Martin ŠrámekCentral Military Hospital in Prague, Prague, Czech Republic.
Nicolas DrenckCopenhagen University Hospital, Copenhagen, Denmark.
Khalid SobhEl hussein Alzahar University Hospital, Cairo, Egypt.
Emilie LesaineCentre Hospitalier de l'Université de Bordeaux, INSERM, Bordeaux Population Health Research Center, CIC-EC 14-01, Bordeaux, France.
Candice SabbenDepartment of Neurology, Rothschild Foundation Hospital, Paris, France.
Peggy ReinerLariboisiere Hospital, Paris, France.
Francois RouanetBordeaux University Hospital Neurology, Stroke Unit, Bordeaux, France.
Daniel StrbianDepartment of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Stefan BoskampDepartment of Neurology, Albertinen Krankenhaus, Hamburg, Germany.
Joshua MbrohDepartment of Neurology & Stroke, Eberhard-Karls University, Tuebingen, Germany.
Simon NagelDepartment of Neurology, Klinikum Ludwigshafen, Ludwigshafen/Rhein, Germany.
Michael RosenkranzDepartment of Neurology, Albertinen Krankenhaus, Hamburg, Germany.
Sven PoliDepartment of Neurology & Stroke, Eberhard-Karls University, Tuebingen, Germany.
Götz ThomallaUniversitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Neurologie, Hamburg, Germany.
Theodoros Karapanayiotides2nd Department of Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, School of Medicine, Faculty of Health Sciences, Thessaloniki, Greece.
Ioanna Koutroulou2nd Department of Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, School of Medicine, Faculty of Health Sciences, Thessaloniki, Greece.
Odysseas KargiotisStroke Unit, Metropolitan Hospital, Piraeus, Greece.
Lina PalaiodimouSecond Department of Neurology, "Attikon" University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
José Dominguo Barrientos GuerraHospital General San Juan de Dios, Guatemala City, Guatemala.
Vikram HudedMazumdar Shaw Medical Center, Bangalore, India.
Shashank NagendraDepartment of Neurology, Grant Medical College and Sir JJ Hospital, Mumbai, India.
Chintan PrajapatiMazumdar Shaw Medical Center, Bangalore, India.
P N SylajaSree Chitra Tirunal Institute for Medical Sciences and Technology, Kerala, India.
Achmad Firdaus SaniDr. Soetomo General Hospital Surabaya, Universitas Airlangga, Surabaya, Indonesia.
Abdoreza GhoreishiDepartment of Neurology, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Mehdi FarhoudiNeurosciences Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Elyar Sadeghi HokmabadiNeurosciences Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Mazyar HashemilarNeurosciences Research Center, Razi Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Sergiu Ionut SabetayNeurology Department, Hillel Yaffe Medical Center, Hadera, Israel.
Fadi RahalHillel Yaffe Medical Center, Hadera, Israel.
Maurizio AcampaStroke Unit, University of Siena, Siena, Italy.
Alessandro AdamiStroke Center IRCCS Sacro Cuore Don Calabria, Verona, Italy.
Marco LongoniNeurology and Stroke Unit, Ospedale Bufalini, Cesena, Italy.
Raffaele OrnelloNeuroscience Section, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Leonardo RenieriInterventional Neurovascular Unit, Careggi University Hospital, Florence, Italy.
Michele RomoliNeurology and Stroke Unit, Department of Neuroscience, Bufalini Hospital, Cesena, Italy.
Simona SaccoNeuroscience Section, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Andrea SalmaggiNeurological Department, "Alessandro Manzoni" Hospital, ASST Lecco, Via dell'Eremo 9/11, Lecco, Italy.
Davide SangalliNeurological Department, "Alessandro Manzoni" Hospital, ASST Lecco, Via dell'Eremo 9/11, Lecco, Italy.
Andrea ZiniIRCCS Istituto delle Scienze Neurologiche di Bologna, Neurologia e Rete Stroke Metropolitana, Bologna, Italy.
Kenichiro SakaiDepartment of Neurology, The Jikei University School of Medicine, Tokyo, Japan.
Hiroki FukudaDepartment of Neurology, Japanese Red Cross Matsue Hospital, Matsue, Japan.
Kyohei FujitaDepartment of Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Hirotoshi ImamuraDepartment of Neurosurgery, Kobe City Medical Center General Hospital, Kobe, Japan.
Miyake KosukeShiroyama Hospital, Shiroyama, Japan.
Manabu SakaguchiDepartment of Neurology, Osaka General Medical Center, Osaka, Japan.
Kazutaka SonodaDepartment of Neurology, Saiseikai Fukuoka General Hospital, Fukuoka, Japan.
Yuji MatsumaruDepartment of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tskukuba, Japan.
Nobuyuki OharaDepartment of Neurology, Kobe City Medical Center General Hospital, Kobe City, Japan.
Seigo ShindoDepartment of Neurology, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan.
Yohei TakenobuOsaka Red Cross Hospital, Osaka, Japan.
Takeshi YoshimotoDepartment of Neurology, National Cerebral and Cardiovascular Center, Osaka, Japan.
Kazunori ToyodaDepartment of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Takeshi UwatokoCerebrovascular Medicine, Stroke Center, Saga Medical Centre Koseikan, Saga, Japan.
Nobuyuki SakaiDepartment of Neurosurgery, Kobe City Medical Center General Hospital, Kobe, Japan.
Nobuaki YamamotoAdvanced Brain Research, Tokushima University, Tokushima, Japan.
Ryoo YamamotoYokohama Brain and Spine Center, Yokohama, Japan.
Yukako YazawaDepartment of Stroke Neurology, Kohnan Hospital, Sendai, Japan.
Yuri SugiuraToyonaka Municipal Hospital, Toyonaka, Japan.
Jang-Hyun BaekDepartment of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Si Baek LeeDepartment of Neurology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, South Korea.
Kwon-Duk SeoDepartment of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, South Korea.
Sung-Il SohnDepartment of Neurology, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, South Korea.
Jin Soo LeeDepartment of Neurology, Ajou University Hospital, Ajou, South Korea.
Anita Ante ArsovskaDepartment of Urgent Neurology, University Clinic of Neurology, University Ss. Cyril and Methodius-Faculty of Medicine, Skopje, North Macedonia.
Chan Yong ChiehHospital Sultan Abdul Halim, Sungai Petani, Malaysia.
Wan Asyraf Wan ZaidiDepartment of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia.
Wan Nur Nafisah Wan YahyaDepartment of Medicine, Pusat Perubatan Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Fernando Gongora-RiveraNeurovascular Unit and Neurology Department, University Hospital Jose Eleuterio Gonzalez, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.
Manuel Martinez-MarinoDepartment of Neurology, Hospital de especialidades del Centro Médico Nacional Siglo XXI IMSS, Mexico City, Mexico.
Adrian Infante-ValenzuelaNeurovascular Unit and Neurology Department, University Hospital Jose Eleuterio Gonzalez, Universidad Autonoma de Nuevo Leon, Monterrey, Mexico.
Diederik DippelDepartment of Neurology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Dianne H K van Dam-NolenDepartment of Neurology, Department of Radiology and Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Teddy Y WuDepartment of Neurology, Christchurch Hospital, Christchurch, New Zealand.
Martin PunterWellington Regional Hospital, Capital and Coast District Health Board, Wellington, New Zealand.
Tajudeen Temitayo AdebayoDepartment of Medical Records, Federal Medical Centre, Owo, Nigeria.
Abiodun H BelloNeurology Unit, University of Ilorin, Ilorin, Nigeria.
Taofiki Ajao SunmonuDepartment of Medicine, Federal Medical Centre Owerri, Neurology Unit, Federal Medical Centre, Owerri, Nigeria.
Kolawole Wasiu WahabNeurology Unit, University of Ilorin, Ilorin, Nigeria.
Antje SundsethDepartment of Neurology, Akershus University Hospital, University of Oslo, Lørenskog, Norway.
Amal M Al HashmiCentral Stroke Unit, Neuroscience Directorate, Khoula Hospital, Ministry of Health, Muscat, Oman.
Saima AhmadLahore General Hospital, Lahore, Pakistan.
Umair RashidLahore General Hospital, Lahore, Pakistan.
Liliana Rodriguez-KadotaDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Essalud, Lima, Peru.
Miguel Ángel VencesDepartamento de Neurología, Hospital Nacional Edgardo Rebagliati Martins, Essalud, Lima, Peru.
Patrick Matic YalungSt. Luke's Medical Center, Global City, Philippines.
Jon Stewart Hao DySt. Luke's Medical Center, Global City, Philippines.
Waldemar BrolaDepartment of Neurology, Specialist Hospital Konskie, Collegium Medicum, Jan Kochanowski University, Kielce, Poland.
Aleksander DębiecClinic of Neurology, Military Institute of Medicine, Warsaw, Poland.
Malgorzata DorobekDepartment of Neurology, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland.
Michal Adam Karlinski2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.
Beata M Labuz-RoszakDepartment of Neurology, St. Jadwiga Provincial Specialist Hospital in Opole, Institute of Medical Sciences, University of Opole, Opole, Poland.
Anetta Lasek-BalDepartment of Neurology, Leszek Giec Upper Silesian Medical Centre of the Silesian Medical University in Katowice, School of Health Sciences, Medical University of Silesia in Katowice, Katowice, Poland.
Halina Sienkiewicz-Jarosz1st Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.
Jacek StaszewskiClinic of Neurology, Military Institute of Medicine, Szasero 128, Warsaw, Poland.
Piotr SobolewskiDepartment of Neurology in Sandomierz, Collegium Medicum, Jan Kochanowski University in Kielce, Sandomierz, Poland.
Marcin WiącekDepartment of Neurology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland.
Justyna Zielinska-TurekDepartment of Neurology, Central Clinical Hospital of the Ministry of Interior and Administration, Warsaw, Poland.
André Pinho AraújoNeuroradiology Department - Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
Mariana RochaNeurology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
Pedro CastroDepartment of Neurology, Centro Hospitalar Universitário de São João, Porto, Portugal.
Patricia FerreiraStroke Unit, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Ana Paiva NunesStroke Unit, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Luísa FonsecaStroke Unit, Medicine Department, Centro Hospitalar Universitário de São João, Porto, Portugal.
Teresa Pinho E MeloHospital de Santa Maria - Centro Hospitalar Lisboa Norte, Lisbon, Portugal.
Miguel RodriguesDepartment of Neurology, Hospital Garcia de Orta, Almada, Portugal.
M Luis SilvaCentro Hospitalar Universitário de São João, Porto, Portugal.
Bogdan CiopleiasCounty Emergency Clinic Hospital Brasov, Brasov, Romania.
Adela DimitriadeBucharest University Emergency Hospital, Bucharest, Romania.
Cristian Falup-PecurariuDepartment of Neurology, County Clinic Hospital, Faculty of Medicine, Transilvania University, Brasov, Romania.
May Adel HamidDepartment of Neurology King Fahad Hospital of the University Imam Abdulrahman bin Faisal University Dammam, Dammam, Saudi Arabia.
Narayanaswamy VenketasubramanianRaffles Hospital, Singapore, Singapore.
Georgi KrastevDepartment of Neurology, Faculty Hospital Trnava, Trnava, Slovakia.
Jozef HaringDepartment of Neurology, Faculty Hospital Trnava, Trnava, Slovakia.
Oscar Ayo-MartinComplejo Hospitalario Universitario de Albacete, Albacete, Spain.
Francisco Hernandez-FernandezComplejo Hospitalario Universitario de Albacete, Albacete, Spain.
Jordi BlascoInterventional Neuroradiology, Hospital Clinic de Barcelona, Barcelona, Spain.
Alejandro Rodríguez-VázquezComprehensive Stroke Center, Hospital Clínic de Barcelona, Barcelona, Spain.
Antonio Cruz-CulebrasDepartment of Neurology (Unidad de Ictus), Hospital Universitario Ramón y Cajal, Madrid, Spain.
Francisco MonicheStroke Unit, Neurology Department, Hospital Universitario Virgen del Rocío, Seville, Spain.
Joan MontanerDepartment of Neurology, Hospital Universitario Virgen Macarena , Seville, Spain.
Soledad Perez-SanchezDepartment of Neurology, Hospital Universitario Virgen Macarena , Seville, Spain.
María Jesús García SánchezDepartment of Neuroradiology, Hospital Universitario Rey Juan Carlos, Madrid, Spain.
Marta Guillán RodríguezDepartment of Neurology, Hospital Universitario Rey Juan Carlos, Madrid, Spain.
Gianmarco BernavaInterventional Neuroradiology, University Hospitals of Geneva, Geneva, Switzerland.
Manuel BologneseNeurocenter, Cantonal Hospital of Lucerne, Lucerne, Switzerland.
Emmanuel CarreraDepartment of Neurology, University Hospitals of Geneva, Geneva, Switzerland.
Anchalee ChurojanaDepartment of Radiology, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Ozlem AykacEskisehir Osmangazi University, Eskisehir, Turkey.
Atilla Özcan ÖzdemirEskisehir Osmangazi University, Eskisehir, Turkey.
Arsida BajramiIstanbul Aydın University, Florya Medicalpark Stroke Center, Istanbul, Turkey.
Songul SenadimIstanbul Aydın University, Florya Medicalpark Stroke Center, Istanbul, Turkey.
Syed I HussainCleveland Clinic Abu Dhabi, Abu Dhabi, United Arabe Emirates.
Seby JohnCleveland Clinic Abu Dhabi, Abu Dhabi, United Arabe Emirates.
Kailash KrishnanStroke, Department of Medicine, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
Robert LenthallNeuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
Kaiz S AsifAmita Health and University of Illinois-Chicago, Chicago, United States.
Kristine BelowNeuroscience and Stroke Program, Bon Secours Mercy Health St Vincent Hospital, Toledo, United States.
Jose BillerLoyola University Chicago Stritch School of Medicine, Maywood, United States.
Michael ChenRush University Medical Center, Chicago, United States.
Alex CheblDepartment of Neurology, Henry Ford Health System, Detroit, United States.
Marco ColasurdoDepartment of Radiology, University of Texas Medical Branch, Galveston, United States.
Alexandra CzapNeurology, McGovern Medical School at the University of Texas Health Science Center, Houston, United States.
Adam H de HavenonUniversity of Utah, Salt Lake City, United States.
Sushrut DharmadhikariBaptist Health Medical Center - Little Rock, Little Rock, United States.
Clifford J EskeyDartmouth Hitchcock Medical Center, Lebanon, United States.
Mudassir FarooquiUniversity of Iowa, Iowa City, United States.
Steven K FeskeNeurology, Boston Medical Center, Boston, USA.
Nitin GoyalDepartment of Neurology, University of Tennessee Health Science Center, Memphis, TN, USA.
Kasey B GrimmettBaptist Health Medical Center - Little Rock, Little Rock, United States.
Amy K GuzikDepartment of Neurology, Wake Forest Baptist Medical Center, Winston-Salem, United States.
Diogo C HaussenDepartment of Neurology, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, United States.
Majesta HovinghDepartment of Neurosciences and Comprehensive Stroke Center, Spectrum Health and Michigan State University College of Human Medicine, Grand Rapids, United States.
Dinesh JillelaDepartment of Neurology, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, United States.
Peter T KanDepartment of Neurosurgery, University of Texas Medical Branch, Galveston, United States.
Rakesh KhatriDepartment of Neurology, Texas Tech University Health Science Center, El Paso, United States.
Naim N KhouryHSHS St. John's Hospital, Southern Illinois University School of Medicine, Springfield, United States.
Nicole L KileyDepartment of Radiology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA.
Murali K KolikondaBaptist Health Medical Group, Baptist Health Lexington, Lexington, United States.
Stephanie LaraCommunity Memorial Hospital, Ventura, United States.
Grace LiUniversity of Florida, Gainesfille, United States.
Italo LinfanteMiami Cardiac & Vascular Institute, Miami Neuroscience Institute, Miami, United States.
Aaron I LoochtanOhio Health Riverside Methodist Hospital, Columbus, United States.
Carlos D LopezSUNY Upstate New York, Syracuse, United States.
Sarah LycanDepartment of Neurology, Wake Forest Baptist Medical Center, Winston-Salem, United States.
Shailesh S MaleDepartment of Neurology & Neurosurgery, Vidant Medical Center, Greenville, United States.
Fadi NahabDepartment of Neurology, Pediatrics, Emory University, Atlanta, United States.
Laith MaaliDepartment of Neurology, University of Kansas Medical Center, Kansas City, United States.
Hesham E MasoudDepartment of Neurology, SUNY Upstate, Syracuse, United States.
Jiangyong MinDepartment of Neurosciences and Comprehensive Stroke Center, Spectrum Health and Michigan State University College of Human Medicine, Grand Rapids, United States.
Santiago Orgeta-GutierrezUniversity of Iowa, Iowa, USA, Iowa City, United States.
Ghada A MohamedDepartment of Neurology, Henry Ford Health System, Detroit, United States.
Mahmoud MohammadenDepartment of Neurology, Emory University School of Medicine, Atlanta, United States.
Krishna NalleballeDepartment of Neurology, University of Arkansas for Medical Sciences, Little Rock, United States.
Yazan RadaidehRush University Medical Center, Chicago, United States.
Pankajavalli RamakrishnanRiverside Regional Medical Center, Newport News, United States.
Bliss Rayo-TarantoSanta Barbara Cottage Hospital, Santa Barbara, United States.
Diana M Rojas-SotoDartmouth Hitchcock Medical Center, Lebanon, United States.
Sean RulandLoyola University Chicago Stritch School of Medicine, Maywood, United States.
Alexis N SimpkinsDepartment of Neurology, University of Florida, Gainesville, United States.
Sunil A ShethNeurology, McGovern Medical School at the University of Texas Health Science Center, Houston, United States.
Amy K StarosciakMiami Neuroscience Institute, Miami, United States.
Nicholas E TarlovCommunity Memorial Hospital, Ventura, United States.
Robert A TaylorSanta Barbara Cottage Hospital, Santa Barbara, United States.
Barbara VoetschDepartment of Neurology, Lahey Health, Burlington, United States.
Linda ZhangDepartment of Neurology, Cooper Neurological Institute, Cooper University Hospital, Camden, USA.
Hai Quang DuongDa Nang Hospital, Da Nang, Vietnam.
Viet-Phuong DaoBach Mai Hospital, Hanoi, Vietnam.
Huynh Vu LeHue Central, Hue, Vietnam.
Thong Nhu PhamDa Nang Hospital, Da Nang, Vietnam.
Mai Duy TonBach Mai Hospital, Hanoi, Vietnam.
Anh Duc TranHue Central, Hue, Vietnam.
Osama O ZaidatNeuroscience and Stroke Program, Bon Secours Mercy Health St Vincent Hospital, Toledo, United States.
Paolo MachiGeneva.
Elisabeth DirrenGeneva.
Claudio Rodríguez FernándezDepartment of Neuroradiology, Hospital Universitario Rey Juan Carlos, Madrid, Spain.
Jorge Escartín LópezDepartment of Neuroradiology, Hospital Universitario Rey Juan Carlos, Madrid, Spain.
Jose Carlos Fernández FerroDepartment of Neuroradiology, Hospital Universitario Rey Juan Carlos, Madrid, Spain.
Niloofar MohammadzadehNeurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Neil C SuryadevaraSUNY Upstate, New York, USA.
Beatriz de la Cruz FernándezHospital Universitario rey Juan Carlos, Spain.
Filipe BessaHospital de Santa Maria - Centro Hospitalar Lisboa Norte, Portugal.
Nina JancarHospital de Santa Maria - Centro Hospitalar Lisboa Norte, Portugal.
Megan BradyDepartment of Neurology, Henry Ford Health System, Detroit, Michigan, USA.
Dawn ScozzariDepartment of Neurology, Henry Ford Health System, Detroit, Michigan, USA.
Boston University · USCooper University Hospital · USImperial College Healthcare NHS Trust · GBMasaryk University · CZUniversity of Lausanne · CHAlexandria University · EGBrown University · USHospital de Egas Moniz · PTHospital de Santa Maria · PTInstitute of Psychiatry and Neurology · PLKU Leuven · BEOsaka National Hospital · JPUniversity of British Columbia · CAUniversity of Colorado Denver · USUniversity of Pittsburgh Medical Center · USUniversity of Tennessee Health Science Center · US
Funding
Bristol-Myers SquibbCerenovusCOST Association CA18118CZECRIN Large Research Infrastructure LM2018128GenentechIschemiaViewMedtronicMinistry of Education, Youth and Sports LTC20051National C-VASC COVID-19 StudyNational Program of Sustainability LQ1605PenumbraSiemens FoundationStrykerSVINTransilvania University BrasovViz.ai
Abstract
background and purposeRecent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year.
methodsWe conducted a cross-sectional retrospective study of 171 stroke centers from 49 countries. We recorded COVID-19 admission volumes, CVT hospitalization, and CVT in-hospital mortality from January 1, 2019, to May 31, 2021. CVT diagnoses were identified by International Classification of Disease-10 (ICD-10) codes or stroke databases. We additionally sought to compare the same metrics in the first 5 months of 2021 compared to the corresponding months in 2019 and 2020 (ClinicalTrials.gov Identifier: NCT04934020).
resultsThere were 2,313 CVT admissions across the 1-year pre-pandemic (2019) and pandemic year (2020); no differences in CVT volume or CVT mortality were observed. During the first 5 months of 2021, there was an increase in CVT volumes compared to 2019 (27.5%; 95% confidence interval [CI], 24.2 to 32.0; P<0.0001) and 2020 (41.4%; 95% CI, 37.0 to 46.0; P<0.0001). A COVID-19 diagnosis was present in 7.6% (132/1,738) of CVT hospitalizations. CVT was present in 0.04% (103/292,080) of COVID-19 hospitalizations. During the first pandemic year, CVT mortality was higher in patients who were COVID positive compared to COVID negative patients (8/53 [15.0%] vs. 41/910 [4.5%], P=0.004). There was an increase in CVT mortality during the first 5 months of pandemic years 2020 and 2021 compared to the first 5 months of the pre-pandemic year 2019 (2019 vs. 2020: 2.26% vs. 4.74%, P=0.05; 2019 vs. 2021: 2.26% vs. 4.99%, P=0.03). In the first 5 months of 2021, there were 26 cases of vaccine-induced immune thrombotic thrombocytopenia (VITT), resulting in six deaths.
conclusionsDuring the 1st year of the COVID-19 pandemic, CVT hospitalization volume and CVT in-hospital mortality did not change compared to the prior year. COVID-19 diagnosis was associated with higher CVT in-hospital mortality. During the first 5 months of 2021, there was an increase in CVT hospitalization volume and increase in CVT-related mortality, partially attributable to VITT.
Indexed as
Cerebral venous thrombosisCOVID-19MortalitySARS-CoV-2StrokeVaccine-induced immune thrombotic thrombocytopenia
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
NCT04934020ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.