Evidence map›Paper›PMID 35677680›Full record

ArticleAcute medicine & surgery

PaO

Akiko Kawakami, Kazuma Yamakawa, Daisuke Nishioka, Koshi Ota, Yusuke Kusaka, Osamu Umegaki, Yuri Ito, Akira Takasu

Open access · goldAbstract read
In one paragraph

Article in Acute medicine & surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Beyond the PaOAnnals of intensive care · 2026
    Review
  3. Combined Use of ECMO, Prone Positioning, and APRV in the Management of Severe COVID-19 Patients.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Akiko KawakamiDepartment of Emergency and Critical Care Medicine Osaka Medical and Pharmaceutical University Takatsuki Japan.
Kazuma YamakawaDepartment of Emergency and Critical Care Medicine Osaka Medical and Pharmaceutical University Takatsuki Japan.ORCID https://orcid.org/0000-0003-2999-4021
Daisuke NishiokaDepartment of Medical Statistics, Research and Development Center Osaka Medical and Pharmaceutical University Takatsuki Japan.
Koshi OtaDepartment of Emergency and Critical Care Medicine Osaka Medical and Pharmaceutical University Takatsuki Japan.
Yusuke KusakaDepartment of Anesthesiology Osaka Medical and Pharmaceutical University Takatsuki Japan.
Osamu UmegakiIntensive Care Unit Osaka Medical and Pharmaceutical University Hospital Takatsuki Japan.
Yuri ItoDepartment of Medical Statistics, Research and Development Center Osaka Medical and Pharmaceutical University Takatsuki Japan.
Akira TakasuDepartment of Emergency and Critical Care Medicine Osaka Medical and Pharmaceutical University Takatsuki Japan.
Osaka University of Pharmaceutical Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Prone positioning of coronavirus disease 2019 (COVID-19) patients could improve oxygenation. However, clinical data on prone positioning of intubated COVID-19 patients are limited. We investigated trends of PaO Methods: This retrospective, observational cohort study was undertaken between April 2020 and May 2021 in a tertiary referral hospital for COVID-19 in Osaka, Japan. We included intubated adult COVID-19 patients treated with prone positioning within the first 72 h of admission to the intensive care unit and followed them until hospital discharge or death. Primary outcomes were in-hospital mortality and escalation of care to ECMO. We used unsupervised k-means clustering modeling to categorize COVID-19 patients by PaO Results: The final study cohort comprised 54 of 155 consecutive severe COVID-19 patients. Three clusters were generated according to trends in PaO Conclusion: In Japanese patients intubated due to COVID-19, clinicians should consider earlier escalation of treatment, such as facility transfer or ECMO, if the PaO

Indexed as

Acute respiratory distress syndromeCOVID‐19ECMOPaO2 / FiO2 ratioprone positioning

Identifiers

PMID35677680
PMCPMC9167425
OpenAlexW4282944135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.