Evidence map›Paper›PMID 35677518›Full record

ReviewJournal of clinical and experimental hepatology

Portal Vein Thrombosis in Cirrhosis.

Akash Shukla, Suprabhat Giri

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Prothrombotic states in portal vein thrombosis and Budd-Chiari syndrome in India: A systematic review and meta-analysis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Pooled it
  2. Portal Vein Thrombosis Risk in Cirrhotic Patients With Portal Hypertension on Beta-Blockers: A Multi-Institutional Cohort Study.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  3. [Pathophysiological mechanisms of coagulation dysfunction associated with liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. [New targets for the prevention and treatment of cirrhotic portal vein thrombosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Shedding Light on the Pathogenesis of Splanchnic Vein Thrombosis.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Akash ShuklaDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, India.
Suprabhat GiriDepartment of Gastroenterology, Seth GS Medical College and KEM Hospital, Mumbai, India.
King Edward Memorial Hospital and Seth G.S. Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with cirrhosis of the liver are at high risk of developing portal vein thrombosis (PVT), which has a complex, multifactorial cause. The condition may present with a myriad of symptoms and can occasionally cause severe complications. Contrast-enhanced computed tomography (CT) is the gold standard for the diagnosis of PVT. There are uncertainties regarding the effect on PVT and its treatment outcome in patients with cirrhosis. The main challenge for managing PVT in cirrhosis is analyzing the risk of hemorrhage compared to the risk of thrombus extension leading to complications. All current knowledge regarding non-tumor PVT in cirrhosis, including epidemiology, risk factors, classification, clinical presentation, diagnosis, impact on natural history, and treatment, is discussed in the present article.

Indexed as

ACLF, acute-on-chronic liver failureanticoagulationBCS, Budd–Chiari syndromecirrhosisDOACs, direct-acting oral anticoagulantsEASL, European Association for the Study of the LivereNOS, endothelial nitric oxide synthaseHCC, hepatocellular carcinomaHVPG, hepatic venous pressure gradientINR, international normalized ratioJAK2, Janus Kinase 2LMWH, low molecular weight heparinLT, liver transplantMELD, Model for End-Stage Liver DiseaseMTHFR, methyltetrahydrofolate reductaseNASH, non-alcoholic steatohepatitisNO, nitric oxidenon-tumoral portal vein thrombosisNSBBs, non-selective beta-blockersportal hypertensionPV, portal veinPVT, Portal vein thrombosisRCT, randomized controlled trialrTPA, recombinant tissue plasminogen activatorSMA, superior mesenteric arterySMV, superior mesenteric veinSVT, splanchnic vein thrombosisTIPS, Transjugular intrahepatic portosystemic shunttransjugular intrahepatic portosystemic shuntUNOS, United Network for Organ SharingVEGF, vascular endothelial growth factorsVKAs, vitamin K antagonistsVKORC1, vitamin K epoxide reductase complex 1vWF, von Willebrand factor

Identifiers

PMID35677518
PMCPMC9168711
OpenAlexW3216126167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.