Evidence map›Paper›PMID 35677507›Full record

ArticleJournal of clinical and experimental hepatology

Nonalcoholic Steatohepatitis: A Rapidly Increasing Indication for Liver Transplantation in India.

Dinesh Jothimani, Silas Danielraj, Gomathy Narasimhan, Ilankumaran Kaliamoorthy, Akila Rajakumar, Kumar Palaniappan, Swetha Palanichamy, Ashwin Rammohan, Hemalatha Ramachandran, Rajesh Rajalingam and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Management of Portal Hypertension in the Older Patient.Current gastroenterology reports · 2024
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Managing HBV and HCV Infection Pre- and Post-liver Transplant.Journal of clinical and experimental hepatology
    Review
  10. Article
  11. Cardiac Evaluation in Liver Transplant Candidates.Journal of clinical and experimental hepatology
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Dinesh JothimaniInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Silas DanielrajInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Gomathy NarasimhanInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Ilankumaran KaliamoorthyInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Akila RajakumarInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Kumar PalaniappanInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Swetha PalanichamyInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Ashwin RammohanInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Hemalatha RamachandranInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Rajesh RajalingamInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Mohamed RelaInstitute of Liver Disease and Transplantation, Dr. Rela Institute and Medical Centre, Bharath Institute of Higher Education and Research, Chromepet, Chennai, Tamilnadu, 600044, India.
Bharath University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Recently, there has been a considerable increase in patients with nonalcoholic fatty liver disease. Availability of high-efficacy drugs for hepatitis B and hepatitis C virus (HCV) infection may have changed the disease prevalence. We aimed to study the impact of this changing epidemiology in patients undergoing liver transplantation (LT) over a 10-year period. Methods: The study population was stratified into Period 1 (2009-2014) and Period 2 (2015-2019). Demographics, indications for LT and changes in the epidemiology between two periods were analysed. Aetiology-based posttransplant survival analysis was carried out. Results: Indication for LT among 1017 adult patients (277 in Period 1 and 740 in Period 2) showed a significant increase in nonalcoholic steatohepatitis (NASH; 85 [30.7%] and 311 [42%]; Conclusion: NASH is the leading indication for liver transplantation in India, surpassing viral hepatitis in recent years.

Indexed as

ASH, Non-alcoholic steatohepatitisCAD, Coronary artery diseasecardiovascular diseaseCLD, Chronic liver diseaseDAA, Direct acting antiviral drugsDM, Diabetes mellitusHBV, Hepatitis B virus infectionHCC, Hepatocellular carcinomaHCV, Hepatitis C virus infectionhepatocellular carcinomaliver transplantationLT, Liver transplantationNAFLD, Non-alcoholic fatty liver diseasenonalcoholic steatohepatitisSVR, Sustained virological responseviral hepatitis

Identifiers

PMID35677507
PMCPMC9168702
OpenAlexW3202114749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.