Evidence map›Paper›PMID 35677382›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Herbal Medicines for the Treatment of Chronic Obstructive Airway Diseases (Asthma or Chronic Obstructive Pulmonary Disease): A Prospective Observational Study.

Yee Ran Lyu, Su-Won Lee, Si-Yeon Kim, Hye-Bin Han, Won-Kyung Yang, Seung-Hyung Kim, In Chul Jung, O-Jin Kwon, Ae-Ran Kim, Jinhee Kim and 2 more

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yee Ran LyuKorean Medicine Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-9823-0618
Su-Won LeeDivision of Respiratory Medicine, Department of Internal Medicine, College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0003-2473-8686
Si-Yeon KimClinical Trial Center, Daejeon Korean Medicine Hospital, Daejeon University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-3467-3444
Hye-Bin HanClinical Trial Center, Daejeon Korean Medicine Hospital, Daejeon University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-8788-1802
Won-Kyung YangDivision of Respiratory Medicine, Department of Internal Medicine, College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-4493-9787
Seung-Hyung KimImmunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-4598-1733
In Chul JungDepartment of Neuropsychiatry, College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0001-7245-4990
O-Jin KwonKorean Medicine Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Ae-Ran KimClinical Medicine Division, R&D Strategy Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Jinhee KimKorean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Mi Young LeeKorean Medicine Convergence Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0001-7337-2460
Yang-Chun ParkDivision of Respiratory Medicine, Department of Internal Medicine, College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-5645-869X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obstructive airway disease is a major health problem and has a great impact on global socioeconomic burden. Despite therapeutic advances in recent decades, there is still a need for effective and safe therapeutic agents for patients with asthma or chronic obstructive pulmonary disease (COPD). Methods: This prospective observational study explored the effects of herbal medicines in patients with asthma and COPD. All participants visited the hospital at least every 4 weeks for 12 weeks to receive their herbal medicines based on their pattern identification and to evaluate safety and efficacy endpoints. We followed the diagnostic criteria used by Korean medicine doctors to prescribe herbal medicines, explored variations in prescribed herbal medicines, and explored a number of clinical features in patients with asthma or COPD. Results: A total of 24 patients were enrolled: 14 were diagnosed with asthma and 10 with COPD and 19 completed the study. After 12 weeks of herbal medicine treatment, herbal medicines significantly improved the modified Clinical Asthma Measurement Scale in Oriental Medicine-V in asthma patients and the modified Medical Research Council Dyspnoea Scale and St. George's Respiratory Questionnaire in COPD patients. For all patients, modified Medical Research Council Dyspnoea Scale score and interleukin-13 were found to be significantly different after treatment. Additionally, the majority of patients were satisfied with our herbal medicine treatments, and no severe adverse events were reported during the study. Conclusions: Our study provides preliminary clinical data on the safety and efficacy of herbal medicines in patients with asthma and COPD.

Identifiers

PMID35677382
PMCPMC9168097

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.