Evidence map›Paper›PMID 35677344›Full record

ArticleInnovation in aging2022

Negative and Positive Psychosocial Factors in Relation to Cognitive Health in Older African Americans.

Maude Wagner, Anne-Josée Guimond, Laura D Kubzansky, Yingzhe Zhang, David A Bennett, Lisa L Barnes, Francine Grodstein

Open access · goldAbstract read
In one paragraph

Article in Innovation in aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Depression, Vascular Burden, and Dementia Prevalence in Late Middle-Aged and Older Black Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Maude WagnerRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-1834-3218
Anne-Josée GuimondDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Laura D KubzanskyDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Yingzhe ZhangDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-3689-554X
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Francine GrodsteinRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Rush University Medical Center · USHarvard University · US

Funding

EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Optimism and Exceptional LongevityR01AG053273 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI GRODSTEIN, FRANCINE, KUBZANSKY, LAURA D · 2016 to 2019
$2.2M
NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG022018NIA NIH HHS R01 AG053273
6 · The paper itself

Abstract

Background and Objectives: Identifying potential intervention strategies to reduce cognitive decline, particularly among older African Americans at high risk for Alzheimer's dementia, is critical. This study aimed to investigate whether depressive symptoms, purpose in life, and their interrelations are associated with cognitive decline in older African Americans. Research Design and Methods: We included older African Americans from the Minority Aging Research Study ( Results: At baseline, each unit increment in depressive symptoms was related to worse initial global cognition (mean difference = -0.03 standard unit; Discussion and Implications: In older African Americans, we found that lower depressive symptoms and greater purpose in life were independently related to higher initial levels of global cognition, but not cognitive decline. Preliminary findings of higher global cognition in individuals with depressive symptoms but greater purpose in life merit further investigation if purpose may eventually be considered as an intervention.

Indexed as

African AmericansCognitive functionDepressive symptomsLinear mixed-effects modelsPurpose in life

Identifiers

PMID35677344
PMCPMC9169895
OpenAlexW4220746677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.