Evidence map›Paper›PMID 35677341›Full record

ArticleFrontiers in neurology2022

The Clinical Utility of the MOCA in iNPH Assessment.

Eric Wesner, Lacey Etzkorn, Shivani Bakre, Jinyu Chen, Alexander Davis, Yifan Zhang, Sevil Yasar, Aruna Rao, Mark Luciano, Jiangxia Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Eric WesnerDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Lacey EtzkornDepartment of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States.
Shivani BakreDepartment of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States.
Jinyu ChenDepartment of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States.
Alexander DavisDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Yifan ZhangDepartment of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States.
Sevil YasarDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Aruna RaoDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Mark LucianoDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Jiangxia WangDepartment of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States.
Abhay MoghekarDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We sought to estimate reliable change thresholds for the Montreal Cognitive Assessment (MoCA) for older adults with suspected Idiopathic Normal Pressure Hydrocephalus (iNPH). Furthermore, we aimed to determine the likelihood that shunted patients will demonstrate significant improvement on the MoCA, and to identify possible predictors of this improvement. Methods: Patients ( Results: All nine of reliable change methods indicated that a 5-point increase in MoCA would be reliable for patients with a baseline MoCA from 16 to 22 (38.4% of patients). Furthermore, a majority of reliable change methods indicated that a 5-point increase in MoCA would be reliable for patients with a baseline MoCA from 14 to 25. Reliable change thresholds varied across methods from 4 to 7 points for patients outside of this range. 10.1% had at least a 5-point increase from baseline to post-TT/ELD. Compared to patients who did not receive a shunt, patients who received a shunt did not have lower average MoCA at baseline ( Conclusions: In patients with iNPH, clinicians could consider using a threshold of 5 points for determining whether iNPH-symptomatic patients have experienced cognitive benefits from cerebrospinal fluid drainage at an individual level. However, a reliable change cannot be detected for patients with a baseline MoCA of 26 or greater, necessitating a different cognitive assessment tool for these patients.

Indexed as

cognitioncognitive examinationMontreal Cognitive Assessment (MoCA)normal pressure hydrocephalusreliable change index (RCI)

Identifiers

PMID35677341
PMCPMC9168991
OpenAlexW4281288741

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.