Evidence map›Paper›PMID 35677314›Full record

ArticleBMJ innovations2022

Design and proof-of-concept evaluation of a touchless connector system for preventing peritoneal dialysis-associated peritonitis.

Ibrahim O Yekinni, Tom Viker, Ryan Hunter, Aaron Tucker, Sarah Elfering, Michelle N Rheault, Arthur Erdman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ innovations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Risk Factors and Pathogen Spectrum in Continuous Ambulatory Peritoneal Dialysis-Associated Peritonitis: A Single Center Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ibrahim O YekinniBakken Medical Devices Center, University of Minnesota, Minnesota, USA.
Tom VikerCerovations LLC, Minnesota, USA.
Ryan HunterDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minnesota, USA.
Aaron TuckerBakken Medical Devices Center, University of Minnesota, Minnesota, USA.
Sarah ElferingDepartment of Medicine, University of Minnesota Medical School, Minnesota, USA.
Michelle N RheaultDepartment of Pediatrics, University of Minnesota Medical School, Minnesota, USA.
Arthur ErdmanBakken Medical Devices Center, University of Minnesota, Minnesota, USA.
University of Minnesota · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
Contamination resistant interconnection for reducing peritoneal dialysis - associated peritonitisR41DK126586 · NIDDK · CEROVATIONS, LLC · PI VIKER, TOM · 2020 to 2020
$314k
NCATS NIH HHS UL1 TR002494NIDDK NIH HHS R41 DK126586
6 · The paper itself

Abstract

Introduction: In this paper, we describe the design of a touchless peritoneal dialysis connector system and how we evaluated its potential for preventing peritoneal dialysis-associated peritonitis, in comparison to the standard of care. The unique feature of this system is an enclosure within which patients can connect and disconnect for therapy, protecting their peritoneal catheters from touch or aerosols. Methods: We simulated a worst-case contamination scenario by spraying 40mL of a standardized inoculum [ 1×10 Results: No contamination was observed in test samples from the touchless connector system, compared to 65%, 75% and 70% incidence contamination for the standard of care on Luria Bertani agar, Mannitol Salts Agar and Pseudomonas isolation agar respectively. Conclusion: Results show that the touchless connector system can prevent fluid path contamination even in heavy bacterial exposures and may help reduce peritoneal dialysis-associated peritonitis risks from inadvertent contamination with further development.

Indexed as

InfectionsNephrologyPeritoneal Diseases

Identifiers

PMID35677314
PMCPMC9173658
OpenAlexW4220669533

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.