Evidence map›Paper›PMID 35677179›Full record

ArticleComputational and mathematical methods in medicine2022

Effects of Tea Treatments against High-Fat Diet-Induced Disorder by Regulating Lipid Metabolism and the Gut Microbiota.

Chen Wang, Jiaxing Liu, Siyao Sang, Xue Ao, Mingjie Su, Binwei Hu, Hui Li

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Nutrition research and practice · 2023
    Article
  3. PPARG: A Novel Target for Yellow Tea in Kidney Stone Prevention.International journal of molecular sciences · 2023
    Article
  4. Observational
  5. Article
  6. Article
  7. Herbal Tea Essences (HTE) Ameliorate HFD-Induced Obesity.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chen WangMOE Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Jiaxing LiuMOE Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Siyao SangMOE Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Xue AoMOE Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Mingjie SuState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China.
Binwei HuMOE Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai 200438, China.
Hui LiMOE Key Laboratory of Contemporary Anthropology, Human Phenome Institute, Fudan University, Shanghai 200438, China.ORCID https://orcid.org/0000-0001-7321-4139
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-fat diet (HFD) may induce changes of metabolism and gut microbiota changes, and these changes are susceptible to diet adjustments such as tea treatment. However, the treatment effects may vary among different types of tea. In this study, we evaluated the effects of six types of tea on glucose and lipid metabolism and gut microbiota in HFD mice. We established HFD mouse model by 12 weeks feed with 60% fat diet, then treated with teas for six weeks. Here, we showed that treatment with different types of tea can inhibit weight gain and insulin resistance though different ways. Green tea regulated lipid metabolism by regulating the expression of adenosine 5'-monophosphate-activated protein kinase (AMPK) and carnitine palmitoyltransferase-I (CPT-1). The effect of dark tea and white tea in reducing liver weight seemed to be related to activities of acetyl-CoA carboxylase (ACC). Yellow tea exhibited the best anti-inflammatory and antioxidant effects and effects of recovering the disorder of model mouse microbiota. The decrease in blood sugar and the upregulation of gluconeogenesis-related enzymes seemed to be related to the decrement of unclassified Lachnospiraceae. These different effects may result from the unique chemical compositions contained by different types of tea, which can regulate different lipid and glucose metabolism-related proteins. Despite variations in its compositions and metabolic reactions, tea is a potent antiobesity and hypoglycemic agent.

Indexed as

Diet, High-FatGastrointestinal MicrobiomeAnimalsHumansLipid MetabolismLiverMiceMice, Inbred C57BLTeaTea

Identifiers

PMID35677179
PMCPMC9168190
OpenAlexW4281768055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.