Evidence map›Paper›PMID 35677155›Full record

ArticleFrontiers in oncology2022

The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.

Lin Xiao, Mawar Karsa, Emma Ronca, Angelika Bongers, Angelika Kosciolek, Ali El-Ayoubi, Jezrael L Revalde, Janith A Seneviratne, Belamy B Cheung, Laurence C Cheung and 12 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. [Recent advances in individualized treatment for pediatric high-risk B-cell acute lymphoblastic leukemia].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
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  7. Updates inBiomedicines · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 8 institutions in 2 countries.

Lin XiaoChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Mawar KarsaChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Emma RoncaChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Angelika BongersChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Angelika KosciolekChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Ali El-AyoubiChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Jezrael L RevaldeChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Janith A SeneviratneChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Belamy B CheungChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Laurence C CheungLeukaemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia.
Rishi S KotechaLeukaemia Translational Research Laboratory, Telethon Kids Cancer Centre, Telethon Kids Institute, Perth, WA, Australia.
Andrea NewboldGene Regulation Laboratory, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Stefan BjelosevicGene Regulation Laboratory, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Greg M ArndtChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Richard B LockChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Ricky W JohnstoneGene Regulation Laboratory, Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
Andrei V GudkovDepartment of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, United States.
Katerina V GurovaDepartment of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, United States.
Michelle HaberChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Murray D NorrisChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Michelle J HendersonChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
Klaartje SomersChildren's Cancer Institute, Lowy Cancer Research Institute, University of New South Wales, Randwick, NSW, Australia.
UNSW Sydney · AUChildren's Cancer Institute Australia · AUPeter MacCallum Cancer Centre · AURoswell Park Comprehensive Cancer Center · USAustralian Cancer Research Foundation · AUCurtin University · AUPrincess Margaret Hospital for Children · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rearrangements of the

Indexed as

chromatincuraxin CBL0137histone deacetylase inhibitioninfant leukemiaKMT2A-rearranged leukemia

Identifiers

PMID35677155
PMCPMC9168530
OpenAlexW4281294445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.