ReviewOxidative medicine and cellular longevity2022
Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives.
Open access · hybridAbstract readReview
In one paragraph
Review in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 2 pooled it
13.3field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 2 syntheses or guidelines pooled it, 164 citations in OpenAlex.
- Effects of oral fenugreek-derived preparations on testosterone-related outcomes in adult men: a systematic review and meta-analysis of randomized placebo-controlled trials.Frontiers in nutrition · 2026Pooled it
- Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use.Nutrients · 2023Pooled it
- How reliable is the labeling of a commercial phytosteroid product? A 12-week randomized double-blind training study.Journal of the International Society of Sports Nutrition · 2025Trial
- Agro-Industrial Potential of Yam (Foods (Basel, Switzerland) · 2026Review
- Comparative Transcriptomic Analysis Provides Insights into PSK-α-Mediated Regulation of Diosgenin Biosynthesis inMolecules (Basel, Switzerland) · 2026Article
- Role of Plant-Derived Antioxidants in Oxidative Stress-Associated Myocardial Infarction: Structure-Activity Relationship (SAR)-Based Mechanistic Insights.Molecules (Basel, Switzerland) · 2026Review
- Solvent-Dependent Metabolomic Profiles and Antioxidant Properties of the Invasive SeaweedPharmaceuticals (Basel, Switzerland) · 2026Article
- Rhizoma Dioscoreae Nipponicae attenuates airway remodeling and angiogenesis-related changes in asthma with altered mTOR/4EBP1/HIF-1α/VEGF pathway markers.The World Allergy Organization journal · 2026Article
- Diosgenin-loaded niosomes ameliorate cadmium-induced neurotoxicity and endocrine disruption in female rats through modulation of oxidative stress, apoptosis, and inflammatory markers.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- A tri-target in silico analysis of Testolift: a nutraceutical formulation targeting aromatase, myostatin, and prolyl hydroxylase-2 in testosterone regulation and muscle performance.Scientific reports · 2026Article
- Diosgenin Attenuates Photoreceptor Degeneration in an N-Methyl-N-Nitrosourea-Induced Mouse Model of Retinal Degeneration.Investigative ophthalmology & visual science · 2026Article
- Dioscin-rich extract of Dioscorea floribunda ameliorates metabolic syndrome by improving inflammation-mediated gut, adipose and hepatic dysfunctions: a pre-clinical study.Inflammopharmacology · 2026Article
- Scale-Up Isolation of High-Purity Shatavarins fromACS omega · 2026Article
- Harnessing Endophytic Fungi as a Sustainable Source of Novel Anticancer Agents: Opportunities, Challenges, and Future Directions.Molecules (Basel, Switzerland) · 2026Review
- Diosgenin-mediated NF-κB and MAPK pathway modulation for osteoarthritis treatment: molecular mechanisms, bioavailability enhancement, and therapeutic applications.Inflammopharmacology · 2026Review
- Risks, Benefits, and Molecular Targets of Fenugreek Administration in the Treatment of Hepatocellular Carcinoma.Cancers · 2026Review
- Harnessing Phytochemicals and Nanotechnology Synergy for Molecular, Epigenetic, and Microbiota-Driven Regulation in Type 2 Diabetes Mellitus.Pharmaceutics · 2026Review
- Mechanism of Babao Dan on fluorouracil-induced bone marrow suppression and T cell immune disorder through MAPK pathway.Scientific reports · 2026Article
- Structural basis for diosgenin as an inverse agonist of retinoic acid receptor-related orphan receptor γ.Scientific reports · 2026Article
- Functional characterization of a novel β-glucosidase converting trillin to diosgenin from Enterococcus faecalis.Microbial cell factories · 2026Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 13 institutions in 10 countries.
Prabhakar SemwalDepartment of Biotechnology, Graphic Era University, Dehradun, 248002 Uttarakhand, India.ORCID https://orcid.org/0000-0001-5137-5169
Sakshi PainuliDepartment of Biotechnology, Graphic Era University, Dehradun, 248002 Uttarakhand, India.
Tareq Abu-IzneidPharmaceutical Sciences Department, College of Pharmacy, Al Ain University, Al Ain 64141, UAE.
Abdur RaufDepartment of Chemistry, University of Swabi, Swabi, Anbar-23561, K.P .K, Pakistan.ORCID https://orcid.org/0000-0003-2429-5491
Anshu SharmaDepartment of Food Science and Technology, Dr. Y.S. Parmar University of Horticulture and Forestry, Nauni, 173230, India.
Sevgi Durna DaştanDepartment of Biology, Faculty of Science, Sivas Cumhuriyet University, 58140 Sivas, Turkey.
Manoj KumarChemical and Biochemical Processing Division, ICAR-Central Institute for Research on Cotton Technology, Mumbai 400019, India.ORCID https://orcid.org/0000-0002-4192-6497
Mohammed M AlshehriPharmaceutical Care Department, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-2041-4695
Yasaman TaheriPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-0836-236X
Rajib DasDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.ORCID https://orcid.org/0000-0001-7852-4080
Saikat MitraDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Talha Bin EmranDepartment of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh.ORCID https://orcid.org/0000-0003-3188-2272
Javad Sharifi-RadPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-7301-8151
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID https://orcid.org/0000-0002-1523-9116
William C ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong.ORCID https://orcid.org/0000-0003-4174-4586
Graphic Era University · INUniversity of Dhaka · BDAl Ain University · AEDaffodil International University · BDDr. Yashwant Singh Parmar University of Horticulture and Forestry · INICAR - Central Institute for Research on Cotton Technology · INNational Guard Health Affairs · SAQueen Elizabeth Hospital · CNShahid Beheshti University of Medical Sciences · IRSivas Cumhuriyet Üniversitesi · TRUniversidad del Azuay · ECUniversity of Medicine and Pharmacy of Craiova · ROUniversity of Swabi · PK
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants including
Indexed as
AsthmaDiosgeninNeoplasmsTrigonellaHumansPhytochemicalsPlant ExtractsDiosgeninPhytochemicalsPlant Extracts
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.