Evidence map›Paper›PMID 35676910›Full record

ArticleClinical neurophysiology practice2022

Eye-opening in brain death: A case report and review of the literature.

Martina Focardi, Barbara Gualco, Maenia Scarpino, Manuela Bonizzoli, Beatrice Defraia, Riccardo Carrai, Giovanni Lanzo, Silvia Raddi, Ilenia Bianchi, Antonello Grippo

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical neurophysiology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Spinal reflexes and brain death.Clinical neurophysiology practice · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Martina FocardiForensic Medical Sciences, Health Sciences Department, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Barbara GualcoForensic Medical Sciences, Health Sciences Department, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Maenia ScarpinoNeurophysiology Unit, Careggi University Hospital, Florence, Italy.
Manuela BonizzoliIntensive Care Unit and Regional ECMO Referral Center, Careggi University Hospital, Florence, Italy.
Beatrice DefraiaForensic Medical Sciences, Health Sciences Department, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Riccardo CarraiNeurophysiology Unit, Careggi University Hospital, Florence, Italy.
Giovanni LanzoNeurophysiology Unit, Careggi University Hospital, Florence, Italy.
Silvia RaddiForensic Medical Sciences, Health Sciences Department, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Ilenia BianchiForensic Medical Sciences, Health Sciences Department, University of Florence, Largo Brambilla 3, 50134 Florence, Italy.
Antonello GrippoNeurophysiology Unit, Careggi University Hospital, Florence, Italy.
Azienda Ospedaliero-Universitaria Careggi · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: According to Italian law, brain death is diagnosed when the patient is in a coma, showing the absence of respiratory drive under specific clinical conditions, and without any brain stem reflexes. On the other hand, presence of spinal reflexes, when correctly identified, does not hamper the diagnosis. Case report: We present a case of eyelid elevation two seconds after thoracic pain stimulation in a patient who otherwise fulfilled all clinical and instrumental brain-death criteria due to a residual preserved function of the superior cervical ganglion. Conclusion: Although the observed reflex is to be considered extracerebral, and therefore it should not hamper the diagnosis of BD, the authors propose implementing cerebral flow evaluation, considered "prudential", as a preliminary assessment before determining BD.

Indexed as

Brain deathCerebral angiographyEyelid elevationPhysical examination spinal reflexes

Identifiers

PMID35676910
PMCPMC9168374
OpenAlexW4280653382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.