Evidence map›Paper›PMID 35676874›Full record

ArticleCartilage

Elevated Patellofemoral and Tibiofemoral T1ρ Relaxation Times Following a First Time Patellar Dislocation.

John J Elias, Mei Li, Mingrui Yang, Richard Lartey, John P Murray, Lutul D Farrow, Carl S Winalski, Xiaojuan Li

Abstract read
In one paragraph

Article in Cartilage. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Associations Between Patient Characteristics and Cartilage T1ρ Relaxation Times Vary Over Time Following Patellar Dislocation.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John J EliasDepartment of Research, Cleveland Clinic Akron General, Akron, OH, USA.ORCID 0000-0002-9298-2915
Mei LiDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0003-3915-4210
Mingrui YangDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA.
Richard LarteyDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0002-8336-7363
John P MurrayDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA.
Lutul D FarrowOrthopaedic & Rheumatologic Institute, Cleveland Clinic, Cleveland, OH, USA.
Carl S WinalskiDepartment of Diagnostic Radiology, Cleveland Clinic, Cleveland, OH, USA.
Xiaojuan LiDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study was performed to evaluate cartilage within the knee following a first-time patellar dislocation, using elevated MRI-based T1ρ relaxation times as an indicator of low proteoglycan concentration. The hypothesis is that MRI-based T1ρ relaxation times for patellofemoral and tibiofemoral cartilage are significantly longer for knees being treated for patellar dislocation than for healthy control knees.

designTwenty-one subjects being treated for a first-time, unilateral dislocation of the patella and 16 healthy controls participated in MRI-based T1ρ relaxation time mapping. Mean relaxation times were quantified for patellofemoral and tibiofemoral regions for injured knees, the contralateral knees, and healthy controls. T1ρ values for each region were compared between the 3 groups with generalized estimating equations. Linear regressions were also performed to correlate T1ρ relaxation times with time from injury.

resultsThe knees with a disloction had longer T1ρ relaxation times than the contralateral knees and control group at the medial patella and longer relaxation times than the control group at the lateral tibia (

conclusionsCompositional changes to cartilage on the medial patella are related to traumatic impact during a dislocation. Potential exists for cartilage properties at the medial patella to improve with time. Cartilage degradation at the lateral tibia is not directly related to traumatic impact. The current baseline data are a starting point to characterize the pathway from a first-time dislocation to progressive cartilage degradation and osteoarthritis.

Indexed as

Cartilage, ArticularJoint DislocationsPatellar DislocationHumansKnee JointPatellaTibiacartilagepatellar dislocationT1ρ

Identifiers

PMID35676874
PMCPMC9189536

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.