ArticleAnalytical and bioanalytical chemistry2022
Rational construction of deep-red fluorescent probe for rapid detection of HClO and its application in bioimaging and paper-based sensing.
Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- A Ratiometric Fast-Response Fluorescent Probe Based on Dicyanoisophorone for Monitoring HClO in Paper Test Strips and Living Mice.Journal of fluorescence · 2025Article
- Ratiometric electrochemiluminescence sensing and intracellular imaging of ClOAnalytical and bioanalytical chemistry · 2024Article
- A novel AIE-based mitochondria-targeting fluorescent probe for monitoring of the fluctuation of endogenous hypochlorous acid in ferroptosis models.Analytical and bioanalytical chemistry · 2024Article
- A novel near-infrared fluorescent probe for rapid sensing of HClO in living cells and zebrafish.Frontiers in chemistry · 2022Article
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Authors and funding
6 authors.
Funding
Abstract
Hypochlorous acid (HClO), the core bactericidal substance of the human immune system, plays a vital role in many physiological and pathological processes in the human body. In this work, we designed and synthesized a novel deep-red fluorescent probe TCF-ClO for the determination of hypochlorous acid through theoretical analysis. The results showed that probe TCF-ClO exhibited excellent characteristics of long-wavelength emission (635 nm), fast response (< 1 min), and low detection limit (24 nM). In addition, it had been successfully used for imaging of HClO in living HeLa cells. More importantly, the TCF-ClO composited paper-based sensing material was successfully constructed. The RGB/gray value was obtained from a mobile phone and computer, which could achieve the quantitative detection of HClO, with a linear detection range of 0-50 μM and a detection limit of 1.09 μM (RGB mode)/3.38 μM (gray mode). The function of the paper-based sensor extended from qualitative to quantitative detection of HClO, and it is expected to become a portable device widely used in the environmental area.
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