ArticleNature2022
Pregnancy enables antibody protection against intracellular infection.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 51 citations in OpenAlex.
- Article
- Immune development in early life.Nature immunology · 2026Review
- Article
- An atlas of human siglecs integrates expression, affinity, and cis/trans sialoglycan recognition profiles.Nature communications · 2026Article
- ESAT-6 and CFP-10 reactive IgG in patients with tuberculosis inhibits intracellular bacteria.Cell reports · 2025Article
- Endothelial cells sialylate IgG within the FcRn-mediated recycling pathway.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Listeriosis.Nature reviews. Disease primers · 2025Review
- Maternal Antibodies to Neurovirulent Pathogens in Fetal Tissues.Annual review of virology · 2025Review
- Lifelong partners: Gut microbiota-immune cell interactions from infancy to old age.Mucosal immunology · 2025Review
- Gut-X axis.iMeta · 2025Review
- Ocular-cerebral immune dialogue: a new perspective and therapeutic potential of regional lymphatic systems.Frontiers in immunology · 2025Review
- B Cell Responses to the Placenta and Fetus.Annual review of pathology · 2025Review
- Pathobiont-driven antibody sialylation through IL-10 undermines vaccination.The Journal of clinical investigation · 2024Article
- Antibodies in breast milk: Pro-bodies designed for healthy newborn development.Immunological reviews · 2024Review
- Regulators of placental antibody transfer through a modeling lens.Nature immunology · 2024Review
- TMEM16F Expressed in Kupffer Cells Regulates Liver Inflammation and Metabolism to Protect Against Listeria Monocytogenes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- From Womb to World: Exploring the Immunological Connections between Mother and Child.ImmunoHorizons · 2024Review
- Sialic acid in the regulation of blood cell production, differentiation and turnover.Immunology · 2024Review
- Vaccines and Monoclonal Antibodies as Alternative Strategies to Antibiotics to Fight Antimicrobial Resistance.International journal of molecular sciences · 2024Review
- Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice.The Journal of clinical investigation · 2024Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
17 authors at 5 institutions in 1 country.
John J EricksonDepartment of Pediatrics, Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0001-6189-9302
Stephanie Archer-HartmannComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
Alexander E YarawskyDepartment of Pediatrics, Division of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-5973-5058
Jeanette L C MillerDepartment of Pediatrics, Division of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.
Stephanie SeveauDepartment of Microbial Infection and Immunity, Ohio State University, Columbus, OH, USA.
Tzu-Yu ShaoDepartment of Pediatrics, Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.
Ashley L SeveranceDepartment of Pediatrics, Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.
Hilary Miller-HandleyDepartment of Pediatrics, Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0001-6805-6025
Yuehong WuDepartment of Pediatrics, Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0003-3590-2090
Giang PhamDepartment of Pediatrics, Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.
Brian R WasikDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.ORCID http://orcid.org/0000-0001-5442-3883
Colin R ParrishDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.ORCID http://orcid.org/0000-0002-1836-6655
Yueh-Chiang HuDepartment of Pediatrics, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-7992-0525
Joseph T Y LauDepartment of Molecular and Cell Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID http://orcid.org/0000-0002-5128-2664
Parastoo AzadiComplex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.
Andrew B HerrDepartment of Pediatrics, Division of Immunobiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.ORCID http://orcid.org/0000-0002-3598-3399
Sing Sing WayDepartment of Pediatrics, Division of Infectious Diseases, Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA. singsing.way@cchmc.org.ORCID http://orcid.org/0000-0001-8948-1952
Cincinnati Children's Hospital Medical Center · USCornell University · USUniversity of Georgia · USRoswell Park Comprehensive Cancer Center · USThe Ohio State University · US
Funding
Impact of the Initial Influenza Exposure on the Quality, Magnitude, Breadth, Potency and Durability of Influenza ImmunityU01AI144673 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI STAAT, MARY A · 2019 to 2025
$36.4MProject 3: Role of Glycosaminoglycans in HematopoiesisP01HL151333 · NHLBI · VERSITI WISCONSIN, INC. · PI HOFFMEISTER, KARIN MARIA · 2021 to 2025
$12.3MPEDIATRIC GASTROENTEROLOGY AND NUTRITION TRAINING GRANTT32DK007727 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Phillip P Minar · 1995 to 2026
$11.3MPediatric Center--Gene Expression /Developmental ScienceK12HD028827 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI Tina Lee Cheng · 2002 to 2026
$9.6MImmunological identity redefined by genetically foreign microchimeric cellsDP1AI131080 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI WAY, SING SING · 2016 to 2020
$5.5MNational Glycoscience Resource- CCRC Service and Training - NGlycoR@CCRCR24GM137782 · NIGMS · UNIVERSITY OF GEORGIA · PI Parastoo Azadi · 2020 to 2026
$5.2MProgesterone induced immune modulation during pregnancy – supplemental research in COVID-19R01AI145840 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI WAY, SING SING · 2019 to 2023
$5.0MSTUDIES OF METAL-DEPENDENT INTERCELLULAR ADHESION IN STAPHYLOCOCCAL BIOFILMSR01GM094363 · NIGMS · UNIVERSITY OF CINCINNATI · PI HERR, ANDREW B · 2011 to 2021
$2.5MMechanisms of staphylococcal skin colonizationR01AI162964 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI PAUL D FEY, ANDREW B HERR · 2022 to 2026
$2.4MMaternal Regulatory T cell antigen-specificityR01AI120202 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI WAY, SING SING · 2016 to 2020
$1.9MFunctional immune tolerance to non-inherited maternal antigenR01AI124657 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI WAY, SING SING · 2017 to 2021
$1.9MMultifaceted activity of listeriolysin O during host cell invasion by ListeriaR01AI107250 · NIAID · OHIO STATE UNIVERSITY · PI SEVEAU, STEPHANIE M M · 2014 to 2018
$1.9MNHLBI NIH HHS P01 HL151333NIAID NIH HHS DP1 AI131080NIAID NIH HHS F32 AI145184NIAID NIH HHS R01 AI107250NIAID NIH HHS R01 AI120202NIAID NIH HHS R01 AI124657NIAID NIH HHS R01 AI145840NIAID NIH HHS R01 AI162964NIAID NIH HHS U01 AI144673NICHD NIH HHS K12 HD028827NIDDK NIH HHS T32 DK007727NIGMS NIH HHS R01 GM094363NIGMS NIH HHS R24 GM137782Wellcome Trust
Abstract
Adaptive immune components are thought to exert non-overlapping roles in antimicrobial host defence, with antibodies targeting pathogens in the extracellular environment and T cells eliminating infection inside cells
Indexed as
Immunity, Maternally-AcquiredImmunoglobulin GIntracellular SpaceListeria monocytogenesMothersPregnancyAcetylesteraseAnimalsAnimals, NewbornB-LymphocytesFemaleInterleukin-10ListeriosisMiceN-Acetylneuraminic AcidSialic Acid Binding Ig-like Lectin 2AcetylesteraseCd22 protein, mouseImmunoglobulin GInterleukin-10N-Acetylneuraminic Acidsialate O-acetylesteraseSialic Acid Binding Ig-like Lectin 2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.