Evidence map›Paper›PMID 35676447›Full record

ArticleScientific reports2022

The cause of acute lethality of mice exposed to a laser-induced shock wave to the brainstem.

Koji Yamamura, Nobuaki Kiriu, Satoshi Tomura, Satoko Kawauchi, Kaoru Murakami, Shunichi Sato, Daizoh Saitoh, Hidetaka Yokoe

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Blast injury simulation in pigs using an air-driven shock wave generator: effects of shock waves of lateral shock wave exposure.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Koji YamamuraDepartment of Oral and Maxillofacial Surgery, National Defense Medical College, Tokorozawa, Japan. yamamura@ndmc.ac.jp.
Nobuaki KiriuDivision of Traumatology, Research Institute, National Defense Medical College, Tokorozawa, Japan.
Satoshi TomuraDivision of Traumatology, Research Institute, National Defense Medical College, Tokorozawa, Japan.
Satoko KawauchiDivision of Bioinformation and Therapeutic Systems, Research Institute, National Defense Medical College, Tokorozawa, Saitama, Japan.
Kaoru MurakamiDepartment of Oral and Maxillofacial Surgery, National Defense Medical College, Tokorozawa, Japan.
Shunichi SatoDivision of Bioinformation and Therapeutic Systems, Research Institute, National Defense Medical College, Tokorozawa, Saitama, Japan.
Daizoh SaitohDivision of Traumatology, Research Institute, National Defense Medical College, Tokorozawa, Japan.
Hidetaka YokoeDepartment of Oral and Maxillofacial Surgery, National Defense Medical College, Tokorozawa, Japan.
National Defense Medical College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Air embolism is generally considered the most common cause of death within 1 h of a blast injury. Shock lung, respiratory arrest, and circulatory failure caused by vagal reflexes contribute to fatal injuries that lead to immediate death; however, informative mechanistic data are insufficient. Here we used a laser-induced shock wave (LISW) to determine the mechanism of acute fatalities associated with blast injuries. We applied the LISW to the forehead, upper neck, and thoracic dorsum of mice and examined their vital signs. Moreover, the LISW method is well suited for creating site-specific damage. Here we show that only mice with upper neck exposure, without damage elsewhere, died more frequently compared with the other injured groups. The peripheral oxygen saturation (SpO

Indexed as

Blast InjuriesRespiratory Distress SyndromeBrain StemHumansLasersLight

Identifiers

PMID35676447
PMCPMC9177849
OpenAlexW4282919776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.