Evidence map›Paper›PMID 35675961›Full record

ArticleBMJ case reports2022

Symptomatic leptomeningeal carcinomatosis: a rare presentation of chronic lymphocytic leukaemia relapse.

Osama Batayneh, Amy Lin, Omar Abu-Jaradeh, Peter Wu, Mauricio F Villamar, Purva Sharma

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Osama BataynehDepartment of Medicine, Kent Hospital/ The Warren Alpert Medical School of Brown University, Providence, RI, USA.ORCID http://orcid.org/0000-0001-8131-2441
Amy LinOMS-III, University of New England College of Osteopathic Medicine, Warwick, RI, USA.
Omar Abu-JaradehDepartment of Medicine, Kent Hospital/ The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Peter WuDepartment of Pathology, Kent Hospital, Warwick, RI, USA.
Mauricio F VillamarDepartment of Neurology, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Purva SharmaDepartment of Hematology and Oncology, Kent Hospital, Warwick, RI, USA Pvsharma@kentri.org.
Brown University · USKent Hospital · USNew England College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central nervous system (CNS) involvement in patients with chronic lymphocytic leukaemia (CLL) is very rare and, when present, it is frequently asymptomatic. Rather, CNS involvement is more common in other haematological malignancies such as mantle cell lymphoma or diffuse large B cell lymphoma. The paucity of literature on CNS involvement in CLL underscores the importance of increasing awareness about its presentation, diagnosis and optimal management. We describe a case of symptomatic leptomeningeal leukaemic involvement as an atypical presentation of CLL relapse. A favourable clinical response was observed following systemic monotherapy with venetoclax.

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellLymphoma, Large B-Cell, DiffuseLymphoma, Mantle-CellMeningeal CarcinomatosisAdultHumansNeoplasm Recurrence, LocalCNS cancerMalignant and Benign haematology

Identifiers

PMID35675961
PMCPMC9185480
OpenAlexW4282933976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.