Evidence map›Paper›PMID 35675933›Full record

ArticleSaudi medical journal2022

Serum neutrophil gelatinase-associated lipocalin concentrations are significantly associated with the severity of COVID-19 in pregnant patients.

Esra Can, Süleyman Cemil Oğlak, Fatma Ölmez, Huri Bulut

Open access · diamondAbstract read
In one paragraph

Article in Saudi medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 3 countries.

Esra CanFrom the Department of Obstetrics and Gynecology (Can, Ölmez), Health Sciences University, Kanuni Sultan Süleyman Training and Research Hospital, from the Department of Medical Biochemistry (Bulut), School of Medicine, Istinye University, Istanbul, and from the Department of Obstetrics and Gynecology (Oğlak), Health Sciences University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Süleyman Cemil OğlakFrom the Department of Obstetrics and Gynecology (Can, Ölmez), Health Sciences University, Kanuni Sultan Süleyman Training and Research Hospital, from the Department of Medical Biochemistry (Bulut), School of Medicine, Istinye University, Istanbul, and from the Department of Obstetrics and Gynecology (Oğlak), Health Sciences University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Fatma ÖlmezFrom the Department of Obstetrics and Gynecology (Can, Ölmez), Health Sciences University, Kanuni Sultan Süleyman Training and Research Hospital, from the Department of Medical Biochemistry (Bulut), School of Medicine, Istinye University, Istanbul, and from the Department of Obstetrics and Gynecology (Oğlak), Health Sciences University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Huri BulutFrom the Department of Obstetrics and Gynecology (Can, Ölmez), Health Sciences University, Kanuni Sultan Süleyman Training and Research Hospital, from the Department of Medical Biochemistry (Bulut), School of Medicine, Istinye University, Istanbul, and from the Department of Obstetrics and Gynecology (Oğlak), Health Sciences University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
University of Health Science · KH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate serum neutrophil gelatinase-associated lipocalin (NGAL) concentrations of pregnant women complicated with coronavirus disease 2019 (COVID-19) and investigate its diagnostic value for the severity of COVID-19.

methodsOf the 46 pregnant women with COVID-19 included in the study, we further classified these women into 2 subgroups: the non-severe COVID-19 group (n=25) and the severe COVID-19 group (n=21).

resultsNeutrophil gelatinase-associated lipocalin plasma concentrations were significantly higher in pregnant women complicated with severe COVID-19 (90 [53.1-207.7] ng/ml) compared to those from pregnant women with non-severe COVID-19 (51.8 [39.6-70.3] ng/ml) and healthy pregnant women (44.3 [32.2-54.1] ng/ml,

conclusionWe demonstrated that NGAL was highly associated with COVID-19 severity. We consider that NGAL might be a useful biomarker to diagnose the disease severity in patients with COVID-19.

Indexed as

COVID-19LipocalinsAcute-Phase ProteinsBiomarkersFemaleHumansLipocalin-2PregnancyProto-Oncogene ProteinsAcute-Phase ProteinsBiomarkersLipocalin-2LipocalinsProto-Oncogene ProteinsCOVID-19disease severityneutrophil gelatinase-associated lipocalin

Identifiers

PMID35675933
PMCPMC9389895
OpenAlexW4281700448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.