Evidence map›Paper›PMID 35675600›Full record

ArticleObstetrics and gynecology2022

Care Levels for Fetal Therapy Centers.

Ahmet A Baschat, Sean B Blackwell, Debnath Chatterjee, James J Cummings, Stephen P Emery, Shinjiro Hirose, Lisa M Hollier, Anthony Johnson, Sarah J Kilpatrick, Francois I Luks and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Obstetrics and gynecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

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  9. Drivers of care and outcomes for people facing fetal conditions in the United States: a conceptual framework.Journal of perinatology : official journal of the California Perinatal Association · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 1 institution in 1 country.

Ahmet A BaschatDepartment of Gynecology & Obstetrics, Johns Hopkins Center for Fetal Therapy, Johns Hopkins University, Baltimore, Maryland; the Department of Obstetrics, Gynecology & Reproductive Sciences and the Division of Pediatric General and Thoracic Surgery, Department of Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas; the Department of Anesthesiology, Children's Hospital Colorado/Colorado Fetal Care Center, University of Colorado School of Medicine, Aurora, Colorado; the Department of Pediatrics & Bioethics, Albany Medical College, Albany, New York; the Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Division of Pediatric, General, Thoracic and Fetal Surgery, Department of Surgery, UC Davis Medical Center, Sacramento, California; the Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, and the Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas; the Department of Obstetrics & Gynecology, Cedars-Sinai Medical Center, Los Angeles, California; the Department of Surgery, Warren Alpert Medical School of Brown University, and Hasbro Children's Hospital, Providence; Rhode Island; the Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, UNC School of Medicine, Chapel Hill, North Carolina; the Center for Fetal Diagnosis and Treatment, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; the Division of Pediatric Cardiology, Department of Clinical Pediatrics, and the Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, San Francisco, California; the Department of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan; the Division of Neonatology, Department of Paediatrics, University of Manitoba, Winnipeg, Manitoba, Canada; the Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota; the Department of Surgery, Centre for Surgical Research, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada; the Division of Newborn Medicine, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, Missouri; Yale University School of Nursing, Orange, Connecticut; and the Ontario Fetal Centre, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
Sean B Blackwell
Debnath Chatterjee
James J Cummings
Stephen P Emery
Shinjiro Hirose
Lisa M Hollier
Anthony Johnson
Sarah J Kilpatrick
Francois I Luks
M Kathryn Menard
Lawrence B McCullough
Julie S Moldenhauer
Anita J Moon-Grady
George B Mychaliska
Michael Narvey
Mary E Norton
Mark D Rollins
Eric D Skarsgard
KuoJen Tsao
Barbara B Warner
Abigail Wilpers
Greg Ryan
Johns Hopkins University · US

Funding

NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
NORTH AMERICAN FETAL THERAPY NETWORK BIANNUAL SCIENTIFIC MEETINGSR13HD059293 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JOHNSON, ANTHONY · 2009 to 2018
$60k
NCATS NIH HHS TL1 TR001864NICHD NIH HHS R13 HD059293
6 · The paper itself

Abstract

Fetal therapies undertaken to improve fetal outcome or to optimize transition to neonate life often entail some level of maternal, fetal, or neonatal risk. A fetal therapy center needs access to resources to carry out such therapies and to manage maternal, fetal, and neonatal complications that might arise, either related to the therapy per se or as part of the underlying fetal or maternal condition. Accordingly, a fetal therapy center requires a dedicated operational infrastructure and necessary resources to allow for appropriate oversight and monitoring of clinical performance and to facilitate multidisciplinary collaboration between the relevant specialties. Three care levels for fetal therapy centers are proposed to match the anticipated care complexity, with appropriate resources to achieve an optimal outcome at an institutional and regional level. A level I fetal therapy center should be capable of offering fetal interventions that may be associated with obstetric risks of preterm birth or membrane rupture but that would be very unlikely to require maternal medical subspecialty or intensive care, with neonatal risks not exceeding those of moderate prematurity. A level II center should have the incremental capacity to provide maternal intensive care and to manage extreme neonatal prematurity. A level III therapy center should offer the full range of fetal interventions (including open fetal surgery) and be able manage any of the associated maternal complications and comorbidities, as well as have access to neonatal and pediatric surgical intervention including indicated surgery for neonates with congenital anomalies.

Indexed as

Fetal TherapiesPremature BirthPremature Rupture of Fetal MembranesChildFemaleHumansInfant, NewbornInfant, PrematurePregnancyPrenatal Care

Identifiers

PMID35675600
PMCPMC9202072
OpenAlexW4281725673

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.