Evidence map›Paper›PMID 35675445›Full record

ArticleJournal of neurophysiology2022

Background suppression of electrical activity is a potential biomarker of subsequent brain injury in a rat model of neonatal hypoxia-ischemia.

A Zayachkivsky, M J Lehmkuhle, J J Ekstrand, F E Dudek

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A ZayachkivskyDepartment of Neurosurgery, University of Utah School of Medicine, Salt Lake City, Utah.ORCID 0000-0002-1704-8882
M J LehmkuhleDepartment of Neurosurgery, University of Utah School of Medicine, Salt Lake City, Utah.
J J EkstrandDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
F E DudekDepartment of Neurosurgery, University of Utah School of Medicine, Salt Lake City, Utah.ORCID 0000-0001-5964-3375
University of Utah · US

Funding

Epoch Telemetry System for Long-Term Monitoring of BiopotentialsR44NS064661 · NINDS · EPITEL, INC. · PI DUDEK, F. EDWARD, LEHMKUHLE, MARK J. · 2011 to 2016
$4.2M
Progression of temporal lobe epilepsyR01NS045144 · NINDS · UNIVERSITY OF UTAH · PI DUDEK, F. EDWARD · 2003 to 2007
$2.2M
Seizure-induced Neuronal Loss and Epileptogenesis in the Immature BrainK08NS070957 · NINDS · UNIVERSITY OF UTAH · PI EKSTRAND, JEFFREY JOHN · 2011 to 2015
$860k
NINDS NIH HHS K08 NS070957NINDS NIH HHS R01 NS045144NINDS NIH HHS R44 NS064661
6 · The paper itself

Abstract

Electrographic seizures and abnormal background activity in the neonatal electroencephalogram (EEG) may differentiate between harmful versus benign brain insults. Using two animal models of neonatal seizures, electrical activity was recorded in freely behaving rats and examined quantitatively during successive time periods with field-potential recordings obtained shortly after the brain insult (i.e., 0-4 days). Single-channel, differential recordings with miniature wireless telemetry were used to analyze spontaneous electrographic seizures and background suppression of electrical activity after

Indexed as

Brain InjuriesEpilepsyHypoxia-Ischemia, BrainAnimalsAnimals, NewbornBiomarkersBrainDisease Models, AnimalElectroencephalographyHypoxiaIschemiaRatsSeizuresBiomarkersbackground EEGepilepsyhypoxianeonatal seizuresseizure

Identifiers

PMID35675445
PMCPMC9273272
OpenAlexW4282916248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.