ArticleScience advances2022
Digital selective transformation and patterning of highly conductive hydrogel bioelectronics by laser-induced phase separation.
Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
What it found
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The trial behind it
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Who cites it
72 citing papers in PubMed.
- Designing PEDOT:PSS hydrogels for bioelectronic interfaces.Materials today (Kidlington, England) · 2026Article
- Micro- and Nanopatterning of Highly Conductive PEDOT Thin Films.Macromolecular rapid communications · 2026Article
- Three-Dimensional Interconnect Technologies for Advanced Flexible Electronics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Laser-Defined States and Hydration-Driven Relaxation in PEDOT:PSS.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- A Xerotic Skin-Compatible Neuromotor Electrode Interface for Non-Invasive Muscle Weakness Evaluation in Dermatomyositis.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- 3D-printed implantable bioelectronics enabled by anti-swelling and biphasic conductive hydrogels.Nature materials · 2026Article
- Advances and Challenges in Wearable Sensors for Health Monitoring.ACS applied materials & interfaces · 2026Review
- Motion Neural Monitoring Based on Flexible Materials: From Signal Acquisition to Training Enhancement.ACS omega · 2026Review
- Ion Compensation-Assisted Photolithography Enables High-Resolution Electrolytes for Neuromorphic Transistors.Nano-micro letters · 2026Article
- Wearable Flexible Sensors for Cardiovascular Disease Monitoring.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Untethered thin-film neurostimulator wrapped around tiny nerve trunks for wireless neuromodulation.Science advances · 2026Article
- Dual-wavelength photopatterning unlocks spatially programmable heterogeneity in liquid crystal elastomers.Nature communications · 2026Article
- Phase-separated hydrogels for advanced biomedical engineering: From material design to applications.Materials today. Bio · 2026Review
- An exceptionally conductive hydrogel for all-organic, ultraflexible, and chronic neural interfaces.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Harnessing Phase Separation for the Development of High-Performance Hydrogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A soft biosensor with printable responsive hydrogel interfaces for detection and differentiation of blood circulation complications.National science review · 2026Article
- Ionic-Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Scaling beyond the vagus nerve: historical and contemporary progress on electrode-based small-diameter peripheral nerve interfaces.Bioelectronic medicine · 2026Review
- Bioinspired Structural Design Enables Synergistic Toughness and Conductivity in Hydrogels for Advanced Wearable Electronics.Nano-micro letters · 2026Article
- Laser Micromachining for Bioelectronics: Past, Present, and Future.Small methods · 2026Review
12 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The patterning of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) hydrogels with excellent electrical property and spatial resolution is a challenge for bioelectronic applications. However, most PEDOT:PSS hydrogels are fabricated by conventional manufacturing processes such as photolithography, inkjet printing, and screen printing with complex fabrication steps or low spatial resolution. Moreover, the additives used for fabricating PEDOT:PSS hydrogels are mostly cytotoxic, thus requiring days of detoxification. Here, we developed a previously unexplored ultrafast and biocompatible digital patterning process for PEDOT:PSS hydrogel via phase separation induced by a laser. We enhanced the electrical properties and aqueous stability of PEDOT:PSS by selective laser scanning, which allowed the transformation of PEDOT:PSS into water-stable hydrogels. PEDOT:PSS hydrogels showed high electrical conductivity of 670 S/cm with 6-μm resolution in water. Furthermore, electrochemical properties were maintained even after 6 months in a physiological environment. We further demonstrated stable neural signal recording and stimulation with hydrogel electrodes fabricated by laser.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.