Evidence map›Paper›PMID 35675289›Full record

ArticlePloS one2022

Radiomics and artificial intelligence in malignant uterine body cancers: Protocol for a systematic review.

Gloria Ravegnini, Martina Ferioli, Maria Abbondanza Pantaleo, Alessio G Morganti, Antonio De Leo, Pierandrea De Iaco, Stefania Rizzo, Anna Myriam Perrone

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gloria RavegniniDepartment of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Martina FerioliRadiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0001-8012-4510
Maria Abbondanza PantaleoDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Alessio G MorgantiRadiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Antonio De LeoDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
Pierandrea De IacoDivision of Oncologic Gynecology, IRCCS-Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Stefania RizzoIstituto di Imaging della Svizzera Italiana (IIMSI), Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.ORCID 0000-0002-5151-0866
Anna Myriam PerroneDivision of Oncologic Gynecology, IRCCS-Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID 0000-0003-3140-4772

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUterine body cancers (UBC) are represented by endometrial carcinoma (EC) and uterine sarcoma (USa). The clinical management of both is hindered by the complex classification of patients into risk classes. This problem could be simplified through the development of predictive models aimed at treatment tailoring based on tumor and patient characteristics. In this context, radiomics represents a method of extracting quantitative data from images in order to non-invasively acquire tumor biological and genetic information and to predict response to treatments and prognosis. Furthermore, artificial intelligence (AI) methods are an emerging field of translational research, with the aim of managing the amount of data provided by the various -omics, including radiomics, through the process of machine learning, in order to promote precision medicine.

objectiveThe aim of this protocol for systematic review is to provide an overview of radiomics and AI studies on UBCs. METHODS AND ANALYSIS: A systematic review will be conducted using PubMed, Scopus, and the Cochrane Library to collect papers analyzing the impact of radiomics and AI on UBCs diagnosis, prognostic classification, and clinical outcomes. The PICO strategy will be used to formulate the research questions: What is the impact of radiomics and AI on UBCs on diagnosis, prognosis, and clinical results? How could radiomics or AI improve the differential diagnosis between sarcoma and fibroids? Does Radiomics or AI have a predictive role on UBCs response to treatments? Three authors will independently screen articles at title and abstract level based on the eligibility criteria. The risk of bias and quality of the cohort studies, case series, and case reports will be based on the QUADAS 2 quality assessment tools.

trial registrationPROSPERO registration number: CRD42021253535.

Indexed as

Artificial IntelligenceSarcomaUterine NeoplasmsFemaleHumansMachine LearningPrecision MedicinePrognosisSystematic Reviews as Topic

Identifiers

PMID35675289
PMCPMC9176798

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.