Evidence map›Paper›PMID 35675085›Full record

SynthesisActa anaesthesiologica Scandinavica2022

Fraction of inspired oxygen during general anesthesia for non-cardiac surgery: Systematic review and meta-analysis.

Maria Høybye, Peter C Lind, Mathias J Holmberg, Maria Bolther, Marie K Jessen, Mikael F Vallentin, Frederik B Hansen, Johanne M Holst, Andreas Magnussen, Niklas S Hansen and 17 more

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Acta anaesthesiologica Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06047119 (Respiratory and Hemodynamic Targets During General Anesthesia - A Randomized Clinical Trial), which is not on this map. Cited by 9 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 5 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06047119 nacompletednot on this mapstarted 2023, after this paper: background citation

Respiratory and Hemodynamic Targets During General Anesthesia - A Randomized Clinical Trial

TypeinterventionalSponsorLars Wiuff AndersenRan2023 to 2025Enrolled485ConditionsPatients Undergoing General AnesthesiaArmsBlood pressure, Positive end expiratory pressure, Tidal volume, Fraction of inspired oxygen
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 5 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 7 institutions in 3 countries.

Maria HøybyeResearch Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark.
Peter C LindDepartment of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark.
Mathias J HolmbergResearch Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-5816-337X
Maria BoltherDepartment of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Marie K JessenResearch Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-9445-7690
Mikael F VallentinDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Frederik B HansenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Johanne M HolstDepartment of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Andreas MagnussenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Niklas S HansenDepartment of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Cecilie M JohannsenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Johannes EnevoldsenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Thomas H JensenDepartment of Internal Medicine, University Hospital of North Norway, Narvik, Norway.
Lara L RoesslerDepartment of Emergency Medicine, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Maibritt P KlitholmDepartment of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Mark A EggertsenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Philip CaapDepartment of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Caroline BoyeDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Karol M DabrowskiDepartment of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Lasse VormfenneDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Jeppe HenriksenDepartment of Anesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Mathias KarlssonDepartment of Anesthesiology and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.
Ida R BallebyNational Hospital of the Faroe Islands, Torshavn, Faroe Islands.
Marie S RasmussenDepartment of Anesthesiology and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.
Kim PaelestikDepartment of Anesthesiology and Intensive Care, Viborg Regional Hospital, Viborg, Denmark.
Asger GranfeldtDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Lars W AndersenResearch Center for Emergency Medicine, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-5752-8082
Aarhus University · DKAarhus University Hospital · DKAalborg University Hospital · DKRegionshospitalet Viborg · DKUniversity Hospital of North Norway · NOUniversity of Southern Denmark · DKUniversity of the Faroe Islands · FO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundControversy exists regarding the effects of a high versus a low intraoperative fraction of inspired oxygen (FiO

methodsPubMed and Embase were searched on March 22, 2022 for randomized clinical trials investigating the effect of different FiO

resultsThis review included 25 original trials investigating the effect of a high (mostly 80%) versus a low (mostly 30%) FiO

conclusionsIn adults undergoing general anesthesia for non-cardiac surgery, a high FiO

Indexed as

OxygenSurgical Wound InfectionAdultAnesthesia, GeneralHumansOxygencomplicationsfraction of inspired oxygengeneral anesthesiameta-analysisoutcomessystematic review

Identifiers

PMID35675085
PMCPMC9543529
OpenAlexW4281731448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.