Evidence map›Paper›PMID 35674863›Full record

ArticleMolecular neurobiology2022

Effects of different probiotic strains B. lactis, L. rhamnosus and L. reuteri on brain-intestinal axis immunomodulation in an endotoxin-induced inflammation.

Monique Michels, Gabriel Fernandes Alves Jesus, Mariane Rocha Abatti, Emily Córneo, Luana Cucker, Heloisa de Medeiros Borges, Natan da Silva Matos, Luana Bezerra Rocha, Rodrigo Dias, Carla Sasso Simon and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Fabrication of bioprints self-coated with thermally sensitive lactobacilli for CAUTI applications.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2026
    Article
  4. Article
  5. ISME communications · 2026
    Article
  6. Review
  7. Article
  8. The Impact ofMicroorganisms · 2024
    Review
  9. Review
  10. Study on the Structure and Bioactivity ofJournal of fungi (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Monique MichelsGabbia Biotechnology, Barra Velha - Santa Catarina, Brazil. moniquemichels@hotmail.com.ORCID http://orcid.org/0000-0001-8440-1976
Gabriel Fernandes Alves JesusGabbia Biotechnology, Barra Velha - Santa Catarina, Brazil.
Mariane Rocha AbattiLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Emily CórneoLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Luana CuckerLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Heloisa de Medeiros BorgesLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Natan da Silva MatosLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Luana Bezerra RochaLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Rodrigo DiasLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Carla Sasso SimonLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Ana Paula Lorenzen VoytenaGabbia Biotechnology, Barra Velha - Santa Catarina, Brazil.
Marina RossettoGabbia Biotechnology, Barra Velha - Santa Catarina, Brazil.
Fernanda RamlovGabbia Biotechnology, Barra Velha - Santa Catarina, Brazil.
Felipe Dal-PizzolLaboratory of Experimental Pathophysiology, Graduate Program in Health Sciences, University of Southern Santa Catarina (UNESC), Criciúma, Brazil.
Centro Universitário do Espírito Santo · BRBiotechnology Research Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study evaluated the effects of supplementation with three different probiotic strains Bifidobacterium lactis (LACT GB™), Lactobacillus rhamnosus (RHAM GB™) and Lactobacillus reuteri (REUT GB™) on brain-intestinal immunomodulation in an animal model of LPS-induced inflammation. Fifty mice Balb/C were distributed into five groups: control; lipopolysaccharide (LPS); LPS + B. lactis (LACT GB™); LPS + L. rhamnosus (RHAM GB™); and LPS + L. reuteri (REUT GB™). The animals were supplemented with their respective probiotic microorganisms daily, for 30 days, at a concentration of 1 × 10

Indexed as

Limosilactobacillus reuteriProbioticsAnimalsBrainEndotoxinsImmunomodulationInflammationLipopolysaccharidesMiceEndotoxinsLipopolysaccharidesGut–brain axisImmunomodulationInflammationProbiotics

Identifiers

PMID35674863
OpenAlexW4281835465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.