Evidence map›Paper›PMID 35674397›Full record

ArticleANZ journal of surgery2022

Frail patients having vascular surgery during the early COVID-19 pandemic experienced high rates of adverse perioperative events and amputation.

Australian and New Zealand Vascular Trial Network (ANZVTN), Sarah J Aitken, Bernard Allard, Nishath Altaf, Noel Atkinson, Omar Aziz, Ruth Battersby, Ruth Benson, Jennifer L Chambers, Gabriella Charlton and 40 more

Abstract read
In one paragraph

Article in ANZ journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Australian and New Zealand Vascular Trial Network (ANZVTN)
Sarah J AitkenConcord Repatriation General Hospital, Sydney, NSW, Australia.ORCID 0000-0002-6701-6213
Bernard AllardWestern Health, Melbourne, VIC, Australia.ORCID 0000-0001-8274-3761
Nishath AltafRoyal Perth Hospital, Perth, WA, Australia.ORCID 0000-0003-3916-0194
Noel AtkinsonRoyal Melbourne Hospital, Melbourne, VIC, Australia.ORCID 0000-0002-0240-1698
Omar AzizNepean Hospital, Sydney, NSW, Australia.ORCID 0000-0002-7671-884X
Ruth BattersbyRoyal Adelaide Hospital, Adelaide, SA, Australia.
Ruth BensonVascular and Endovascular Research Network, Birmingham, UK.
Jennifer L ChambersPort Macquarie Base Hospital, Port Macquarie, NSW, Australia.
Gabriella CharltonConcord Repatriation General Hospital, Sydney, NSW, Australia.ORCID 0000-0003-0927-115X
Chloe ColemanThe Alfred Hospital, Melbourne, VIC, Australia.ORCID 0000-0002-0940-0452
Joseph A DawsonRoyal Adelaide Hospital, Adelaide, SA, Australia.ORCID 0000-0001-9229-9545
Anastasia DeanThe Alfred Hospital, Melbourne, VIC, Australia.ORCID 0000-0001-5313-8001
Bedanta S DhalFiona Stanley Hospital, Perth, WA, Australia.ORCID 0000-0001-5466-7570
Robert FitridgeRoyal Adelaide Hospital, Adelaide, SA, Australia.
John GanPort Macquarie Base Hospital, Port Macquarie, NSW, Australia.
Joseph HannaRoyal Perth Hospital, Perth, WA, Australia.ORCID 0000-0003-3609-4136
Andrew T HattamRoyal Melbourne Hospital, Melbourne, VIC, Australia.ORCID 0000-0002-9073-4694
Martin HeinRoyal Perth Hospital, Perth, WA, Australia.ORCID 0000-0003-2720-2043
Kay HonRoyal Adelaide Hospital, Adelaide, SA, Australia.ORCID 0000-0002-8661-776X
Samantha KhooConcord Repatriation General Hospital, Sydney, NSW, Australia.ORCID 0000-0001-9458-2029
Joseph KilbyUniversity Hospital Geelong, Geelong, VIC, Australia.ORCID 0000-0001-8263-9286
Beatrice KuangRoyal Adelaide Hospital, Adelaide, SA, Australia.ORCID 0000-0002-0339-4389
Kai Wen LeongRoyal Melbourne Hospital, Melbourne, VIC, Australia.ORCID 0000-0003-4610-8503
Eunice LimConcord Repatriation General Hospital, Sydney, NSW, Australia.ORCID 0000-0002-4736-6355
Ju-Wei N LiuConcord Repatriation General Hospital, Sydney, NSW, Australia.
David N McClureUniversity Hospital Geelong, Geelong, VIC, Australia.ORCID 0000-0001-6784-2008
Shreya MehtaConcord Repatriation General Hospital, Sydney, NSW, Australia.ORCID 0000-0002-2486-6023
Jana-Lee MossFiona Stanley Hospital, Perth, WA, Australia.ORCID 0000-0003-3846-7944
Juanita MullerPrincess Alexandra Hospital, Brisbane, QLD, Australia.
Korana MusickiRoyal Melbourne Hospital, Melbourne, VIC, Australia.ORCID 0000-0003-1476-9948
Sandip NandhraVascular and Endovascular Research Network, Birmingham, UK.
Michael J PapanikolasConcord Repatriation General Hospital, Sydney, NSW, Australia.ORCID 0000-0003-4450-4983
Fernando Picazo PinedaRoyal Perth Hospital, Perth, WA, Australia.ORCID 0000-0003-0944-7784
Franklin PondWestern Health, Melbourne, VIC, Australia.ORCID 0000-0002-2599-6428
Nandhini RavintharanThe Alfred Hospital, Melbourne, VIC, Australia.ORCID 0000-0001-8835-8864
Toby RichardsFiona Stanley Hospital, Perth, WA, Australia.ORCID 0000-0001-9872-4653
Hani SaeedWestern Health, Melbourne, VIC, Australia.ORCID 0000-0002-3526-0705
Christopher N SelvarajPort Macquarie Base Hospital, Port Macquarie, NSW, Australia.ORCID 0000-0003-3222-8539
Gurkirat SinghNepean Hospital, Sydney, NSW, Australia.ORCID 0000-0003-2995-4193
Yogeesan SivakumaranRoyal Adelaide Hospital, Adelaide, SA, Australia.ORCID 0000-0002-4692-2313
Bethany M StavertConcord Repatriation General Hospital, Sydney, NSW, Australia.ORCID 0000-0002-4726-0868
Elizabeth SuthersPort Macquarie Base Hospital, Port Macquarie, NSW, Australia.ORCID 0000-0002-5547-4452
Robert TangNepean Hospital, Sydney, NSW, Australia.ORCID 0000-0003-4302-0231
Vincent C VarleyThe Alfred Hospital, Melbourne, VIC, Australia.ORCID 0000-0003-3949-3108
Thodur M VasudevanThe Alfred Hospital, Melbourne, VIC, Australia.ORCID 0000-0002-1599-7726
Uyen G VoFiona Stanley Hospital, Perth, WA, Australia.ORCID 0000-0002-6340-9263
Timothy WagnerRoyal Melbourne Hospital, Melbourne, VIC, Australia.ORCID 0000-0001-8763-4206
Judy WangUniversity Hospital Geelong, Geelong, VIC, Australia.ORCID 0000-0002-7355-7542
Jackie WongRoyal Perth Hospital, Perth, WA, Australia.ORCID 0000-0002-6313-0449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrailty predicts adverse perioperative outcomes and increased mortality in patients having vascular surgery. Frailty assessment is a potential tool to inform resource allocation, and shared decision-making about vascular surgery in the resource constrained COVID-19 pandemic environment. This cohort study describes the prevalence of frailty in patients having vascular surgery and the association between frailty, mortality and perioperative outcomes.

methodsThe COVID-19 Vascular Service in Australia (COVER-AU) prospective cohort study evaluates 30-day and six-month outcomes for consecutive patients having vascular surgery in 11 Australian vascular units, March-July 2020. The primary outcome was mortality, with secondary outcomes procedure-related outcomes and hospital utilization. Frailty was assessed using the nine-point visual Clinical Frailty Score, scores of 5 or more considered frail.

resultsOf the 917 patients enrolled, 203 were frail (22.1%). The 30 day and 6 month mortality was 2.0% (n = 20) and 5.9% (n = 35) respectively with no significant difference between frail and non-frail patients (OR 1.68, 95%CI 0.79-3.54). However, frail patients stayed longer in hospital, had more perioperative complications, and were more likely to be readmitted or have a reoperation when compared to non-frail patients. At 6 months, frail patients had twice the odds of major amputation compared to non-frail patients, after adjustment (OR 2.01; 95% CI 1.17-3.78), driven by a high rate of amputation during the period of reduced surgical activity.

conclusionOur findings highlight that older, frail patients, experience potentially preventable adverse outcomes and there is a need for targeted interventions to optimize care, especially in times of healthcare stress.

Indexed as

COVID-19FrailtyAgedAmputation, SurgicalAustraliaCohort StudiesFrail ElderlyGeriatric AssessmentHumansLength of StayPandemicsPostoperative ComplicationsProspective StudiesRisk FactorsVascular Surgical ProceduresamputationCOVID-19frailtyvascular surgery procedures

Identifiers

PMID35674397
PMCPMC9347445

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.