Evidence map›Paper›PMID 35674331›Full record

ArticleChembiochem : a European journal of chemical biology2022

Histidine Ligated Iron-Sulfur Peptides.

Luca Valer, Daniele Rossetto, Taylor Parkkila, Lorenzo Sebastianelli, Graziano Guella, Amber L Hendricks, James A Cowan, Lingzi Sang, Sheref S Mansy

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Iron: Life's primeval transition metal.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Protocellular Heme and Iron-Sulfur Clusters.Accounts of chemical research · 2024
    Review
  5. Article
  6. Paramagnetic NMR to study iron sulfur proteins:Journal of biomolecular NMR · 2023
    Article
  7. CysB Is a Key Regulator of the Antifungal Activity ofInternational journal of molecular sciences · 2023
    Article
  8. Histidine Ligated Iron-Sulfur Peptides.Chembiochem : a European journal of chemical biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Luca ValerD-CIBIO, University of Trento, via Sommarive 9, 38123, Trento 28123, Italy.ORCID 0000-0002-0952-2433
Daniele RossettoD-CIBIO, University of Trento, via Sommarive 9, 38123, Trento 28123, Italy.ORCID 0000-0002-9399-0888
Taylor ParkkilaDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, T6G 2G2, Alberta, Canada.
Lorenzo SebastianelliDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, T6G 2G2, Alberta, Canada.
Graziano GuellaDepartment of Physics, University of Trento, Via Sommarive 14, Trento, 38123, Italy.ORCID 0000-0002-1799-0819
Amber L HendricksDepartment of Chemistry and Biochemistry, The Ohio State University, 100 West 18th Ave, Columbus, OH 43210, USA.
James A CowanDepartment of Chemistry and Biochemistry, The Ohio State University, 100 West 18th Ave, Columbus, OH 43210, USA.
Lingzi SangDepartment of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, T6G 2G2, Alberta, Canada.ORCID 0000-0002-1052-8947
Sheref S MansyD-CIBIO, University of Trento, via Sommarive 9, 38123, Trento 28123, Italy.ORCID 0000-0003-2382-198X
University of Alberta · CAThe Ohio State University · USUniversity of Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron-sulfur clusters are thought to be ancient cofactors that could have played a role in early protometabolic systems. Thus far, redox active, prebiotically plausible iron-sulfur clusters have always contained cysteine ligands to the cluster. However, extant iron-sulfur proteins can be found to exploit other modes of binding, including ligation by histidine residues, as seen with [2Fe-2S] Rieske and MitoNEET proteins. Here, we investigated the ability of cysteine- and histidine-containing peptides to coordinate a mononuclear Fe

Indexed as

HistidineIron-Sulfur ProteinsCysteineIronPeptidesSulfurCysteineHistidineIronIron-Sulfur ProteinsPeptidesSulfurbioinorganic chemistryiron-sulfur clustersmetallopeptidesprebiotic chemistryRieske

Identifiers

PMID35674331
PMCPMC9400863
OpenAlexW4281620403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.