Evidence map›Paper›PMID 35674052›Full record

ArticleJournal of the American Geriatrics Society2022

Optimism, lifestyle, and longevity in a racially diverse cohort of women.

Hayami K Koga, Claudia Trudel-Fitzgerald, Lewina O Lee, Peter James, Candyce Kroenke, Lorena Garcia, Aladdin H Shadyab, Elena Salmoirago-Blotcher, JoAnn E Manson, Francine Grodstein and 1 more

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Affect regulation and allostatic load over time.Psychoneuroendocrinology · 2024
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Hayami K KogaDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0002-9716-2502
Claudia Trudel-FitzgeraldDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0001-9989-4259
Lewina O LeeNational Center for Posttraumatic Stress Disorder at VA Boston Healthcare System, Boston, Massachusetts, USA.ORCID 0000-0002-1652-8198
Peter JamesDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.ORCID 0000-0002-2858-1973
Candyce KroenkeDivision of Research, Kaiser Permanente, Oakland, California, USA.ORCID 0000-0002-6128-3118
Lorena GarciaDepartment of Public Health Sciences, School of Medicine, University of California-Davis, Davis, California, USA.ORCID 0000-0002-9976-761X
Aladdin H ShadyabDepartment of Family Medicine and Public Health, University of California, San Diego School of Medicine, La Jolla, California, USA.ORCID 0000-0002-9693-0522
Elena Salmoirago-BlotcherBrown University School of Medicine, Providence, Rhode Island, USA.ORCID 0000-0003-4636-8698
JoAnn E MansonDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-9426-7595
Francine GrodsteinRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.ORCID 0000-0002-2699-7051
Laura D KubzanskyDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0002-4039-2235

Funding

Optimism and Exceptional LongevityR01AG053273 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI GRODSTEIN, FRANCINE, KUBZANSKY, LAURA D · 2016 to 2019
$2.2M
Lifespan Effects of Biologically Embedded Stress on HealthK08AG048221 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LEE, LEWINA ONYI · 2015 to 2019
$645k
NIA NIH HHS K08 AG048221NIA NIH HHS R01 AG053273
6 · The paper itself

Abstract

backgroundResearch has suggested optimism is associated with healthy aging and exceptional longevity, but most studies were conducted among non-Hispanic White populations. We examined associations of optimism to longevity across racial and ethnic groups and assessed healthy lifestyle as a possible mediating pathway.

methodsParticipants from the Women's Health Initiative (N = 159,255) completed a validated measure of optimism and provided other demographic and health data at baseline. We evaluated associations of optimism with increments in lifespan using accelerated failure time models, and with likelihood of exceptional longevity (survival to age ≥90) using Poisson regression models. Causal mediation analysis explored whether lifestyle-related factors mediated optimism-lifespan associations.

resultsAfter covariate adjustment, the highest versus lowest optimism quartile was associated with 5.4% (95% confidence interval [CI] = 4.5, 6.4%) longer lifespan. Within racial and ethnic subgroups, these estimates were 5.1% (95%CI = 4.0, 6.1%) in non-Hispanic White, 7.6% (95%CI = 3.6, 11.7%) in Black, 5.4% (95%CI = -0.1, 11.2%) in Hispanic/Latina, and 1.5% (95% CI = -5.0, 8.5) in Asian women. A high proportion (53%) of the women achieved exceptional longevity. Participants in the highest versus lowest optimism quartile had greater likelihood of achieving exceptional longevity (e.g., full sample risk ratio = 1.1, 95%CI = 1.1, 1.1). Lifestyle mediated 24% of the optimism-lifespan association in the full sample, 25% in non-Hispanic White, 10% in Black, 24% in Hispanic/Latina, and 43% in Asian women.

conclusionsHigher optimism was associated with longer lifespan and a greater likelihood of achieving exceptional longevity overall and across racial and ethnic groups. The contribution of lifestyle to these associations was modest. Optimism may promote health and longevity in diverse racial and ethnic groups. Future research should investigate these associations in less long-lived populations.

Indexed as

Health PromotionLongevityEthnicityFemaleHispanic or LatinoHumansLife Styleaginglongevityoptimismpsychological well-beingrace/ethnicity

Identifiers

PMID35674052
PMCPMC9588526

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.