ArticleCirculation. Cardiovascular imaging2022
Accuracy and Reproducibility of Myocardial Blood Flow Quantification by Single Photon Emission Computed Tomography Imaging in Patients With Known or Suspected Coronary Artery Disease.
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Article in Circulation. Cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 52 citations in OpenAlex.
- Chronic remote ischemic conditioning treatment in patients with chronic stable angina (EARLY-MYO-CSA): a randomized, controlled proof-of-concept trial.BMC medicine · 2023Trial
- Quantitative and semi-quantitative comparison of myocardial blood flow betweenQuantitative imaging in medicine and surgery · 2026Article
- Feasibility of Quantitative Myocardial Perfusion with CZT SPECT and SPECT/CT: Current Limitations and Recommendations for Future Improvements.Current cardiology reports · 2026Review
- Diagnostic and prognostic value of myocardial flow reserve quantification with single photon emission computed tomography - a systematic review and meta-analysis.EJNMMI research · 2025Article
- Coronary microvascular dysfunction in systemic inflammatory diseases: From pathophysiology and prevalence to diagnosis and management.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2025Review
- Advances in Imaging Techniques for Assessing Myocardial Microcirculation in People with Diabetes : An Overview of Current Techniques, Emerging Techniques, and Clinical Applications.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Review
- Comparison of global and regional myocardial blood flow quantification using dynamic solid-state detector SPECT and Tc-99 m-sestamibi or Tc-99 m-tetrofosmin in a routine clinical setting.The international journal of cardiovascular imaging · 2025Article
- Modeling cardiac microcirculation for the simulation of coronary flow and 3D myocardial perfusion.Biomechanics and modeling in mechanobiology · 2024Article
- The diagnostic role of resting myocardial blood flow in STEMI patients after revascularization.Frontiers in cardiovascular medicine · 2024Article
- The prognostic value of CZT SPECT stress myocardial blood flow (MBF) quantification-opportunity for stress-first/stress-only protocol.European journal of nuclear medicine and molecular imaging · 2024Article
- Future of Radionuclide Myocardial Perfusion Imaging: Transitioning from SPECT to PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Article
- Exploring coronary microvascular function by quantitative CZT-SPECT: a small step or giant leap for INOCA patients?European journal of nuclear medicine and molecular imaging · 2023Article
- Utility of myocardial blood flow assessment with dynamic CZT single photon emission computed tomography in patients with myocardial bridging: Is this 'wishful thinking' in this dynamic situation?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- The potential of dynamicEuropean heart journal open · 2023Article
- Radiolabeling and Biological Evaluation of NovelPharmaceutics · 2022Article
- Improved detection of coronary artery disease by CZT regional coronary blood flow evaluation.Frontiers in nuclear medicine · 2022Article
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Authors and funding
19 authors at 6 institutions in 4 countries.
Ana Carolina do A H de SouzaCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).ORCID 0000-0001-6613-7542
Hendrik J HarmsCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Laurel MartellCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Courtney BibboCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Meagan HarringtonCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Kyle SullivanCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Jon HainerCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).ORCID 0000-0002-0572-912X
Sharmila DorbalaCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Ron BlanksteinCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Viviany R TaquetiCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Marie Foley KijewskiCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Mi-Ae ParkCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).ORCID 0000-0003-0806-129X
Alejandro MerettaInstituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina (A.M.).
Christopher BreaultCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Nathaniel RothSpectrum Dynamics Medical, Caesarea, Israel (C.B., N.R.).
Alexis Poitrasson-RivièreINVIA Medical Imaging Solutions, Ann Harbor' MI (A.P.-R.).ORCID 0000-0002-6960-9389
Prem SomanHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA (P.S.).
Grant T GullbergDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA (G.T.G.).
Marcelo F Di CarliCardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
Brigham and Women's Hospital · USClinical Solutions · USInstituto de Neurología de Buenos Aires · ARSpectrum Dynamics Medical (Switzerland) · CHUniversity of California, San Francisco · USUniversity of Pittsburgh Medical Center · US
Funding
Noninvasive Cardiovascular Imaging Research Training ProgramT32HL094301 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Marcelo F DI CARLI · 2010 to 2026
$7.8MExtension to Coronary Flow Reserve to Assess Hidden Risk: Focus on Women, Heart Failure, and InflammationK23HL135438 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI TAQUETI, VIVIANY R · 2017 to 2021
$1.1MNHLBI NIH HHS K23 HL135438NHLBI NIH HHS T32 HL094301
Abstract
backgroundSingle photon emission computed tomography (SPECT) has limited ability to identify multivessel and microvascular coronary artery disease. Gamma cameras with cadmium zinc telluride detectors allow the quantification of absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR). However, evidence of its accuracy is limited, and of its reproducibility is lacking. We aimed to validate
methodsAccuracy was assessed in 34 participants who underwent dynamic
resultsSPECT global MBF with splines showed good correlation with
conclusionsMBF and MFR quantification using
Indexed as
Coronary Artery DiseaseMyocardial Perfusion ImagingAmmoniaCadmiumCoronary CirculationHumansPositron-Emission TomographyReproducibility of ResultsTechnetium Tc 99m SestamibiTomography, Emission-Computed, Single-PhotonZincAmmoniaCadmiumTechnetium Tc 99m SestamibiZincmyocardial blood flowmyocardial flow reservepositron emission tomographytomography, emission-computed, single-photon
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.