Evidence map›Paper›PMID 35674000›Full record

ArticleExperimental neurobiology2022

Deletion of Phospholipase C β1 in the Thalamic Reticular Nucleus Induces Absence Seizures.

Bomi Chang, Junweon Byun, Ko Keun Kim, Seung Eun Lee, Boyoung Lee, Key-Sun Kim, Hoon Ryu, Hee-Sup Shin, Eunji Cheong

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Bomi ChangCenter for Cognition and Sociality, Institute for Basic Science, Daejeon 34126, Korea.
Junweon ByunCenter for Cognition and Sociality, Institute for Basic Science, Daejeon 34126, Korea.
Ko Keun KimCenter for Cognition and Sociality, Institute for Basic Science, Daejeon 34126, Korea.
Seung Eun LeeBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Boyoung LeeCenter for Cognition and Sociality, Institute for Basic Science, Daejeon 34126, Korea.
Key-Sun KimBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Hoon RyuBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Hee-Sup ShinCenter for Cognition and Sociality, Institute for Basic Science, Daejeon 34126, Korea.
Eunji CheongDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Institute for Basic Science · KRKorea Institute of Science and Technology · KRKorea Institute of Brain Science · KRKorean Association Of Science and Technology Studies · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Absence seizures are caused by abnormal synchronized oscillations in the thalamocortical (TC) circuit, which result in widespread spike-and-wave discharges (SWDs) on electroencephalography (EEG) as well as impairment of consciousness. Thalamic reticular nucleus (TRN) and TC neurons are known to interact dynamically to generate TC circuitry oscillations during SWDs. Clinical studies have suggested the association of

Indexed as

Absence seizurePlcβ1Spike and wave dischargesThalamic reticular nucleusThalamocortical neuronal system

Identifiers

PMID35674000
PMCPMC9194639
OpenAlexW4282841512

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.