Evidence map›Paper›PMID 35673910›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2022

[Hyperoside protects mouse spermatocytes GC-2 cells from oxidative damage by activating the Keap1/Nrf2/HO-1 pathway].

Y Zhu, T Wang, N Dai, M Deng, H Liu, X Tong, L Li

Open access · greenAbstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. [Antioxidant activity ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Y ZhuDepartment of Pharmacology, College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230012, China.
T WangDepartment of Pharmacology, College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230012, China.
N DaiDepartment of Andrology, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230601, China.
M DengDepartment of Pharmacology, College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230012, China.
H LiuDepartment of Pharmacology, College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230012, China.
X TongDepartment of Pharmacology, College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230012, China.
L LiDepartment of Pharmacology, College of Integrated Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230012, China.
Anhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the protective effect of hyperoside (Hyp) against ydrogen peroxide (H

methodsGC-2 cells were treated with 2.5 mmol/L azaacetylcysteine (NAC), 50, 100, and 200 μmol/L hyperoside, or the culture medium for 48 h before exposure to H

resultsExposure to H

conclusionHyperoside protects GC-2 cells against H

Indexed as

Heme Oxygenase-1NF-E2-Related Factor 2AnimalsAntioxidantsHydrogen PeroxideKelch-Like ECH-Associated Protein 1MaleMiceOxidative StressQuercetinRNA, MessengerSpermatocytesSuperoxide DismutaseAntioxidantsHeme Oxygenase-1Hydrogen PeroxidehyperosideKeap1 protein, mouseKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2QuercetinRNA, MessengerSuperoxide DismutaseGC-2 cellsHO-1hyperosideKeap1Nrf2oxidative stress

Identifiers

PMID35673910
PMCPMC9178631
OpenAlexW4282926254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.